Dystrophin Antibody
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Catalog number3586R-100
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PricePlease ask
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Size100 µg
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Antibody TargetDystrophin
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Target Alternative NameDMD , DXS272 , DXS269 , DXS230 , Dystrophin, DXS268 , DXS270 , DXS239, DXS142 , CMD3B , DXS206 , DXS164 , BMD
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide surrounding amino acid 3656 of human Dystrophin
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AccessionNP_004002.2
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Gene Id1756
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-Dystrophin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~60 and 130 kDa of Dystrophin in samples from human, mouse and rat origins. Reactivity to other species has not been determined.
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DescriptionDystrophin is one of the actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin expression is found in muscle brain tissues, where it is located to the inner surface of the plasma membrane. It is sμggested that alternative splicing of the caboxy terminus allows dystrophin to interact with a variety of proteins. Loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and lack of dystrophin results in the loss of linkage between the cytoskeleton and extracellular matrix.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDRP2, DAG1, SGCB
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Short nameDystrophin Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameDystrophin (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namedystrophin related protein 2
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GenBank acession
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Locus
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Discovery year1996-07-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers ZZ-type
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namedystroglycan 1
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Synonyms gene name
- dystroglycan 1 (dystrophin-associated glycoprotein 1)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-07-22
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesarcoglycan beta
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Synonyms gene
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Synonyms gene name
- sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-01-24
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data