Cilomilast

• Catalog number
  B2182-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  cis-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid; SB 207499, SB-207499; Ariflo
• Description
  Cilomilast is an orally active, second-generation phosphodiesterase (PDE) inhibitor that may be effective in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It has high selectivity for the cyclic AMP-specific, or PDE4, isoenzyme that predominates in pro-inflammatory and immune cells and is ten-fold more selective for PDE4D than for PDE4A, B and C.
• CAS Number
  153259-65-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₂₅NO₄
• Molecular Weight
  343.42
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~15 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A PDE4 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  151170
• PubChem CID Link
• SMILES
  COC1=C(C=C(C=C1)C2(CCC(CC2)C(=O)O)C#N)OC3CCCC3
• InChi
  InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)
• InChi Key
  CFBUZOUXXHZCFB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Cilomilast  
• Short name
  Cilomilast
• Alternative name
  Cilomilast

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