Caspase-14 Antibody

  • Catalog number
    3011-100
  • Supplier
  • Price
    487.42 USD
  • Size
    100 µg
  • Antibody Target
    Caspase-14
  • Target Alternative Name
    CASP-14
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human
  • Immunogen Sequence
    Synthetic peptide corresponding sequence surrounding amino acid 176 of human Caspase-14
  • Accession
    P31944
  • Gene Id
    23581
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
  • Purification
    Affinity purified
  • Application
    Western blot
  • Positive Control
    Jurkat cell lysate
  • Application And Usages
    Western blot (1:100)
  • Description
    Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Additional description
    Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    CASP14, CARD14
  • Short name
    Caspase-14 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    caspase-14 (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Caspase 14 Antibody - Gentaur.com
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