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Alternative_name
CV-11974,1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
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Description
Candesartan is an oral angiotensin II receptor blocker (IC50 values are 1.12 and 2.86 nM in bovine adrenal cortex and rabbit aorta, respectively). It is available as a pro-drug, candesartan cilexetil, which undergoes hydrolysis in the gastrointestinal tract during absorption to its active form. Displays antihypertensive effects in animal models.
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CAS Number
139481-59-7
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₄H₂₀N₆O₃
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Molecular Weight
440.45
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Cell Permeable
True
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Purity
≥98% by HPLC
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Solubilities
>40 mg/ml DMSO
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Handling
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag Line
An oral angiotensin II receptor blocker
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
36 months
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PubChem CID
2541
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SMILES
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O
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InChi
InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
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InChi Key
HTQMVQVXFRQIKW-UHFFFAOYSA-N
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MSDS Available
1