Camptothecin
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Catalog number1039-50MG
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PricePlease ask
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Size50 mg
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Alternative_name(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
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DescriptionReversibly inhibits nuclear topoisomerase I by binding to and stabilizing the topoisomerase-DNA covalent complex. Inhibits Tat-mediated transcription of HIV-1. Induces apoptosis in Jurkat, osteosarcoma and hepatoma cells.
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CAS Number7689-03-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₀H₁₆N₂O₄
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Molecular Weight348.4
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Cell PermeableYes
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Purity>98% by TLC
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SolubilitiesDMSO (10 mg/ml)
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HandlingProtect from light and moisture
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Tag LineA topoisomerase I inhibitor
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Storage Condition-20°C
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Shipping ConditionRT
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Shelf Life12 months
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MDL NumberMFCD00081076
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PubChem CID24360
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SMILESCCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
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InChiInChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
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InChi KeyVSJKWCGYPAHWDS-FQEVSTJZSA-N
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MSDS AvailableYes
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Gene target
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Short nameCamptothecin
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Alternative nameCamptothecin
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