Camptothecin

• Catalog number
  1039-50MG
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
• Description
  Reversibly inhibits nuclear topoisomerase I by binding to and stabilizing the topoisomerase-DNA covalent complex. Inhibits Tat-mediated transcription of HIV-1. Induces apoptosis in Jurkat, osteosarcoma and hepatoma cells.
• CAS Number
  7689-03-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₁₆N₂O₄
• Molecular Weight
  348.4
• Cell Permeable
  Yes
• Purity
  >98% by TLC
• Solubilities
  DMSO (10 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  A topoisomerase I inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  RT
• Shelf Life
  12 months
• MDL Number
  MFCD00081076
• PubChem CID
  24360
• PubChem CID Link
• SMILES
  CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
• InChi
  InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
• InChi Key
  VSJKWCGYPAHWDS-FQEVSTJZSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Camptothecin  
• Short name
  Camptothecin
• Alternative name
  Camptothecin

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