BMP-13, human recombinant

  • Catalog number
    4639-1000
  • Price
    Please ask
  • Size
    1 mg
  • Synonyms
    bone morphogenetic protein 13, GDF-6, Cartilage-Derived Morphogenetic Protein-2, CDMP-2
  • Alternative_names
    bone morphogenetic protein 13, GDF-6, Cartilage-Derived Morphogenetic Protein-2, CDMP-2
  • Description
    A TGF-beta family protein involved in patterning of the epidermis and bone & joint formation
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥95%
  • Assay
    SDS-PAGE
  • Biological activity
    The ED₅₀ as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is in the range of 2-3 µg/ml.
  • Results
    2-3 µg/ml
  • Molecular Weight
    27 kDa
  • Storage Temp
    -20°C
  • Shipping
    Blue ice
  • Shelf Life
    12 months
  • Appearance
    Lyophilized protein
  • Physical form description
    Sterile filtered and lyophilized with no additives
  • Reconstitution Instructions
    Reconstitute to 0.1-1.0 mg/ml in H₂O containing BSA (50 ug BSA per 1 ug of protein).
  • Background Information
    BMPs (bone morphogenetic proteins) belong to the TGF-b superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. BioVision’s recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    BMP-13  
  • Gene symbol
    PIRC58, SNORD114-13, SNORD115-13, IGLV3-13, GDF11, IGHV3OR16-13, GDF10, ERVK-13, SNORD116-13, GDF6
  • Short name
    BMP-13, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    BMP-13, H. sapiens Rec.
  • Alternative technique
    rec
Gene info
  • Identity
  • Gene
  • Long gene name
    piwi-interacting RNA cluster 58
  • Locus
    13
  • Discovery year
    2009-11-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin lambda variable 3-13 (pseudogene)
  • Synonyms gene name
    • immunoglobulin lambda variable 3-13
    • immunoglobulin lambda variable 3-13 pseudogene
  • GenBank acession
  • Locus
  • Discovery year
    2000-05-08
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin lambda locus at 22q11.2
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    endogenous retrovirus group K member 13
  • Synonyms gene name
    • endogenous retrovirus group K, member 13
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2011-05-05
  • Pubmed identfication
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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