Anidulafungin

• Catalog number
  B2966-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl] -11,20,21,25-tetrahydroxy-3,15-bis[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexazatricyclo [22.3.0.09,13]heptacosan-18-yl]-4-[4-(4-pentoxyphenyl)phenyl]benzamide; Eraxis; Ecalta; LY303366; 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B
• Description
  Anidulafungin is an echinocandin antifungal drug. It inhibits (1→3)-β-D-glucan synthase which is required for synthesis of the fungal cell wall. It shows potent in vitro activity against Aspergillus and Candida species (MIC₅₀ of 0.03 to 4 μg/ml), including those resistant to fluconazole or amphotericin B. It is effective in treating esophageal candidiasis in clinical trials and has an excellent safety profile.
• CAS Number
  166663-25-8
• Structure Available
  True
• Salt Form
  false
• Molecular Formula
  C₅₈H₇₃N₇O₁₇
• Molecular Weight
  1140.24
• Cell Permeable
  False
• Purity
  ≥95%
• Solubilities
  ~10 mg/ml in DMSO and DMF in 0
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  An antifungal drug that inhibits (1→3)-β-D-glucan synthase
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00917070
• PubChem CID
  166548
• PubChem CID Link
• SMILES
  CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)NC4CC(C(NC(=O)C5C(C(CN5C(=O)C(NC(=O)C(NC(=O)C6CC(CN6C(=O)C(NC4=O)C(C)O)O)C(C(C7=CC=C(C=C7)O)O)O)C(C)O)C)O)O)O
• InChi
  InChI=1S/C58H73N7O17/c1-5-6-7-24-82-40-22-18-35(19-23-40)33-10-8-32(9-11-33)34-12-14-37(15-13-34)51(74)59-41-26-43(70)54(77)63-56(79)47-48(71)29(2)27-65(47)58(81)45(31(4)67)61-55(78)46(50(73)49(72)36-16-20-38(68)21-17-36)62-53(76)42-25-39(69)28-64(42)57(80)44(30(3)66)60-52(41)75/h8-23,29-31,39,41-50,54,66-73,77H,5-7,24-28H2,1-4H3,(H,59,74)(H,60,75)(H,61,78)(H,62,76)(H,63,79)/t29-,30+,31+,39+,41-,42-,43+,44-,45-,46-,47-,48-,49-,50-,54+/m0/s1
• InChi Key
  JHVAMHSQVVQIOT-MFAJLEFUSA-N
• Data Sheet Link
• MSDS Available
  True

• Gene target
  Anidulafungin  
• Short name
  Anidulafungin
• Alternative name
  Anidulafungin

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