1400W dihydrochloride

• Catalog number
  2055-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-(3-(Aminomethyl)benzyl)acetamidine . 2HCl
• Description
  Cell-permeable. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd ≤ 7 nM). In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with Kᵢ values of 2 and 50 µM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices.
• CAS Number
  214358-33-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₀H₁₅N₃ . 2HCl
• Molecular Weight
  250.17
• Cell Permeable
  Yes
• Purity
  ≥98% by NMR
• Solubilities
  Water (100 mM)
• Handling
  Protect from air and moisture
• Tag Line
  A highly selective iNOS inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD03428622
• PubChem CID
  2733515
• PubChem CID Link
• SMILES
  CC(=NCC1=CC(=CC=C1)CN)N.Cl.Cl
• InChi
  InChI=1S/C10H15N3.2ClH/c1-8(12)13-7-10-4-2-3-9(5-10)6-11;;/h2-5H,6-7,11H2,1H3,(H2,12,13);2*1H
• InChi Key
  WDJHSQZCZGPGAA-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  1400W   dihydrochloride  
• Short name
  1400W dihydrochloride
• Alternative name
  1400W dihydrochloride

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