Thyroid peroxidase Antibody

• Catalog number
  bs-0447R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Thyroid peroxidase Primary Polyclonal Antibody
• Also known as
  Thyroid peroxidase PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Thyroid peroxidase
• Specificity
  This is a highly specific antibody against Thyroid peroxidase.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  375-425/914
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from mouse Thyroid peroxidase
• Gene ID number
  22018
• Swiss Prot
  P35419
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Thyroid peroxidase; TPO
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugate
  Peroxidases with EC number 1.11.1.x are catalyzing the reaction of ROOR' + electron donor (2 e−) + 2H+ → ROH + R'OH
• French translation
  anticorps

• Gene target
  Thyroid  
• Gene symbol
  THRB, PTCSC3, TRIP13
• Short name
  Anti-Thyroid peroxidase
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Label
  peroxidase
• Alternative name
  Thyroid peroxidase Polyclonal Antibody
• Alternative technique
  antibodies
• Tissue
  thyroid

Gene info

• Identity
  HGNC:11799
• Gene
  THRB
• Long gene name
  thyroid hormone receptor beta
• Synonyms gene
  • ERBA2
  • PRTH
• Synonyms gene name
  • thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)
  • pituitary resistance to thyroid hormone
  • thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
  • thyroid hormone receptor, beta
• Synonyms
  • THRB1
  • THRB2
  • NR1A2
  • THR1
  • ERBA-BETA
  • GRTH
  • TRbeta
• Synonyms name
  • avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2
  • oncogene ERBA2
  • generalized resistance to thyroid hormone
  • thyroid hormone receptor beta 1
• Locus
  3p24.2
• Discovery year
  1988-08-31
• Entrez gene record
  7068
• Pubmed identfication
  • 1973914
  • 8040303
• RefSeq identity
  • NM_000461
• Classification
  • Thyroid hormone receptors
• VEGA ID
  OTTHUMG00000130478

Gene info

• Identity
  HGNC:43959
• Gene
  PTCSC3
• Long gene name
  papillary thyroid carcinoma susceptibility candidate 3
• Synonyms gene name
  • papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
• GenBank acession
  • JN689234
  • CB987890
• Locus
  14q13.3
• Discovery year
  2012-05-11
• Entrez gene record
  100886964
• Pubmed identfication
  • 22586128
  • 26274343
  • 29561707
• RefSeq identity
  • NR_049735
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000170617

Gene info

• Identity
  HGNC:12307
• Gene
  TRIP13
• Long gene name
  thyroid hormone receptor interactor 13
• Synonyms
  • 16E1BP
• Synonyms name
  • thyroid receptor interacting protein 13
• GenBank acession
  • L40384
• Locus
  5p15.33
• Discovery year
  2000-01-04
• Entrez gene record
  9319
• Pubmed identfication
  • 7776974
• RefSeq identity
  • NM_004237
• Classification
  • AAA ATPases
• VEGA ID
  OTTHUMG00000090349

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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