NSD1 Antibody

• Catalog number
  bs-8170R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NSD1 Primary Polyclonal Antibody
• Also known as
  NSD1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NSD1
• Specificity
  This is a highly specific antibody against NSD1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NSD1
• Gene ID number
  64324
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Androgen receptor coactivator 267 kDa protein; Androgen receptor-associated protein of 267 kDa; ARA267; H3 K36 HMTase; H3-K36-HMTase; H4 K20 HMTase; H4-K20-HMTase; Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specic; KMT3B; Lysine N-methyltransferase 3B; NR binding SET domain containing protein; NR-binding SET domain-containing protein; Nsd1; NSD1_HUMAN; Nuclear receptor binding SET domain containing protein 1; Nuclear receptor-binding SET domain-containing protein 1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NSD1  
• Gene symbol
  NSD1
• Short name
  Anti-NSD1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NSD1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14234
• Gene
  NSD1
• Long gene name
  nuclear receptor binding SET domain protein 1
• Synonyms gene
  • STO
• Synonyms gene name
  • Sotos syndrome
• Synonyms
  • ARA267
  • FLJ22263
  • KMT3B
• GenBank acession
  • AK026066
• Locus
  5q35.3
• Discovery year
  2002-02-25
• Entrez gene record
  64324
• Pubmed identfication
  • 9628876
  • 11896389
• RefSeq identity
  • NM_172349
• Classification
  • PHD finger proteins
  • Lysine methyltransferases
  • PWWP domain containing
• VEGA ID
  OTTHUMG00000130846
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_512

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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