MGMT Antibody
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Catalog numberbs-1002R
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PricePlease ask
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Size0.1ml
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Long nameMGMT Primary Polyclonal Antibody
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Also known asMGMT PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenMGMT
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SpecificityThis is a highly specific antibody against MGMT.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationNucleus
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MGMT
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Gene ID number4255
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Swiss ProtP16455
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenInvolved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesMethylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMGMT
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Short nameAnti-MGMT
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameMGMT Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetO-6-methylguanine-DNA methyltransferase, MGMT and IDBG-93188 and ENSG00000170430 and 4255, DNA-methyltransferase activity, nuclei, Mgmt and IDBG-211408 and ENSMUSG00000054612 and 17314
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Gene info
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Identity
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Gene
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Long gene nameO-6-methylguanine-DNA methyltransferase
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-10-16
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Entrez gene record
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RefSeq identity
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Classification
- Methyltransferases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data