human Fibrinogen Antibody

  • Catalog number
    bs-1240R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    human Fibrinogen Primary Polyclonal Antibody
  • Also known as
    human Fibrinogen PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    human Fibrinogen
  • Specificity
    This is a highly specific antibody against human Fibrinogen.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    Fibrinogen from human plasma
  • Gene ID number
    2243
  • Swiss Prot
    P02671
  • Tested Applications
    ELISA
  • Recommended dilutions
    ELISA(1:500-1000)
  • Cross reactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    Fib2; Fibrinogen alpha chain; FGA
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    FGG, FGB, FGA
  • Short name
    Anti-human Fibrinogen
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Species
    Human, Humans
  • Alternative name
    human Fibrinogen Polyclonal Antibody
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
    FGB
  • Long gene name
    fibrinogen beta chain
  • Synonyms gene name
    • fibrinogen, B beta polypeptide
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Fibrinogen C domain containing
    • Receptor ligands
  • VEGA ID
  • Locus Specific Databases
Gene info
  • Identity
  • Gene
    FGA
  • Long gene name
    fibrinogen alpha chain
  • Synonyms gene name
    • fibrinogen, A alpha polypeptide
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Fibrinogen C domain containing
    • Receptor ligands
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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