Glutathione S Transferase alpha Antibody
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Catalog numberbs-13398R
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PricePlease ask
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Size0.1ml
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Long nameGlutathione S Transferase alpha Antibody
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Also known asGlutathione S Transferase alpha Antibody
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenGSTA1/Glutathione S Transferase alpha
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SpecificityThis is a highly specific antibody against GSTA1/Glutathione S Transferase alpha.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GSTA1/Glutathione S Transferase alpha
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Gene ID number2938
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenMembers of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. GSTs are differentially expressed in lung, liver and kidney tissue. Three isoforms, GSTA1-1, GSTA1-4 and GSTM1, localize to the mitochondria in addition to the cytoplasm. In normal and transformed cells, the oncoprotein Myb transcriptionally upregulates GSTM1. This isoform shows high specific activity for aflatoxin B1 epoxide conjugation, suggesting an important role for this interaction in the defense against both chemical and oxidative stress. The C-terminal domain of GSTA1 may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesGlutathione S alkyltransferase A1; Glutathione S aralkyltransferase A1; Glutathione S aryltransferase A1; Glutathione S transferase 2; Glutathione S transferase A1; Glutathione S transferase alpha 1; Glutathione S transferase Ha subunit 1; Glutathione S-transferase A1; GST 2; GST class alpha; GST class alpha 1; GST class alpha member 1; GST class-alpha member 1; GST epsilon; GST HA subunit 1; GST, class alpha, 1; GST-epsilon; GST2; GSTA 1; GSTA1 1; GSTA1; GSTA1 protein; GSTA1-1; GSTA1_HUMAN; GTH 1; GTH1; HA subunit 1; MGC131939; OTTHUMP00000016611; S hydroxyalkylglutathione lyase A1.
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DescriptionThe Anti-GSTA1/Glutathione S Transferase alpha is a α- or alpha protein sometimes glycoprotein present in blood.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolGSTA5, GSTA1, GSTA3
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Short nameAnti-GSTA1/Glutathione S Transferase alpha
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameGlutathione S Transferase alpha Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameglutathione S-transferase alpha 5
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Synonyms gene name
- glutathione S-transferase A5
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GenBank acession
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Locus
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Discovery year2002-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Soluble glutathione S-transferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglutathione S-transferase alpha 1
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Synonyms gene name
- glutathione S-transferase A1
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Locus
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Discovery year1991-12-06
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Entrez gene record
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Pubmed identfication
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Classification
- Soluble glutathione S-transferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglutathione S-transferase alpha 3
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Synonyms gene name
- glutathione S-transferase A3
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GenBank acession
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Locus
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Discovery year1994-04-29
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Entrez gene record
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Pubmed identfication
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Classification
- Soluble glutathione S-transferases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data