Glutaredoxin 2 Antibody
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Catalog numberbs-13394R
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PricePlease ask
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Size0.1ml
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Long nameGlutaredoxin 2 Primary Polyclonal Antibody
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Also known asGlutaredoxin 2 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenGlutaredoxin 2
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SpecificityThis is a highly specific antibody against Glutaredoxin 2.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range120-164/164
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Subcellular locationNucleus, Mitochondrion
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glutaredoxin 2
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Gene ID number51022
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Swiss ProtQ9NS18
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Tested ApplicationsIHC-P, IF(IHC-P)
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Recommended dilutionsIHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenGlutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesGRX2; CGI-133; Glutaredoxin-2, mitochondrial; GLRX2
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolGLRX2, GLRXP2, GRXCR2
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Short nameAnti-Glutaredoxin 2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameGlutaredoxin 2 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameglutaredoxin 2
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Synonyms gene name
- glutaredoxin (thioltransferase) 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Glutaredoxin domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglutaredoxin pseudogene 2
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Synonyms gene name
- glutaredoxin (thioltransferase) pseudogene 2
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GenBank acession
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Locus
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Discovery year2002-12-19
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglutaredoxin and cysteine rich domain containing 2
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Synonyms gene name
- glutaredoxin, cysteine rich 2
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Synonyms
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Locus
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Discovery year2008-09-11
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Entrez gene record
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Pubmed identfication
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Classification
- Glutaredoxin domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data