Coxsackie Adenovirus Receptor Antibody
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Catalog numberbs-2389R
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PricePlease ask
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Size0.1ml
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Long nameCoxsackie Adenovirus Receptor Antibody
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Also known asCoxsackie Adenovirus Receptor Antibody
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenCoxsackie Adenovirus Receptor
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SpecificityThis is a highly specific antibody against Coxsackie Adenovirus Receptor.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range20-70/365
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor
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Gene ID number1525
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Swiss ProtP78310
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Tested ApplicationsWB, FCM, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenComponent of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCAR; HCAR; CAR4/6; Coxsackievirus and adenovirus receptor; CVB3-binding protein; Coxsackievirus B-adenovirus receptor; HCVADR; CXADR
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolCXADRP3, CXADRP2, CXADRP1
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Short nameAnti-Coxsackie Adenovirus Receptor
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameCoxsackie Adenovirus Receptor Antibody
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Alternative techniqueantibodies
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Virusadenovirus, coxsackie
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Gene info
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Identity
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Gene
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Long gene nameCXADR pseudogene 3
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Synonyms gene name
- coxsackie virus and adenovirus receptor pseudogene 3
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Locus
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Discovery year2008-01-31
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCXADR pseudogene 2
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Synonyms gene name
- coxsackie virus and adenovirus receptor pseudogene 2
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Locus
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Discovery year2008-01-31
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCXADR pseudogene 1
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Synonyms gene name
- coxsackie virus and adenovirus receptor pseudogene 1
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Synonyms
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Locus
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Discovery year2008-01-31
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Entrez gene record
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data