AFAP1L2 Antibody

• Catalog number
  bs-11020R
• Price
  Please ask
• Size
  0.1ml

• Long name
  AFAP1L2 Primary Polyclonal Antibody
• Also known as
  AFAP1L2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  AFAP1L2
• Specificity
  This is a highly specific antibody against AFAP1L2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AFAP1L2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  KIAA1914; XB130; Actin filament-associated protein 1-like 2; AF1L2_HUMAN; AFAP1-like protein 2; afap1l2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AFAP1L2  
• Gene symbol
  AFAP1L2
• Short name
  Anti-AFAP1L2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  AFAP1L2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  actin filament associated protein 1-like 2, AFAP1L2 and IDBG-90372 and ENSG00000169129 and 84632, SH2 domain binding, Cytoplasm, Afap1l2 and IDBG-179434 and ENSMUSG00000025083 and 226250, AFAP1L2 and IDBG-640002 and ENSBTAG00000004895 and 615436

Gene info

• Identity
  HGNC:25901
• Gene
  AFAP1L2
• Long gene name
  actin filament associated protein 1 like 2
• Synonyms gene
  • KIAA1914
• Synonyms gene name
  • KIAA1914
  • actin filament associated protein 1-like 2
• Synonyms
  • FLJ14564
  • Em:AC005383.4
  • XB130
• GenBank acession
  • BC024314
• Locus
  10q25.3
• Discovery year
  2004-02-18
• Entrez gene record
  84632
• Pubmed identfication
  • 11572484
  • 17412687
• RefSeq identity
  • NM_032550
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000019086

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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