ADAMTS8 Antibody
-
Catalog numberbs-5859R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameADAMTS8 Primary Polyclonal Antibody
-
Also known asADAMTS8 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenADAMTS8
-
SpecificityThis is a highly specific antibody against ADAMTS8.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAMTS8
-
Gene ID number11095
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesA disintegrin and metalloproteinase with thrombospondin mots 8; ADAMTS 8; METH 2; METH 8; METH8; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot 8; A disintegrin like and metalloprotease with thrombospondin type 1 mot 8; ADAM metallopeptidase with thrombospondin type 1 mot 8; ADAM TS 8; ADAM TS8; METH2; ATS8_HUMAN.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolADAMTS8
-
Short nameAnti-ADAMTS8
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameADAMTS8 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Alternative to gene targetADAM metallopeptidase with thrombospondin type 1 motif, 8, ADAM-TS8 and METH2, ADAMTS8 and IDBG-76259 and ENSG00000134917 and 11095, low affinity phosphate transmembrane transporter activity, Extracellular, Adamts8 and IDBG-146397 and ENSMUSG00000031994 and 30806, ADAMTS8 and IDBG-642991 and ENSBTAG00000010411 and 512544
-
Gene info
-
Identity
-
Gene
-
Long gene nameADAM metallopeptidase with thrombospondin type 1 motif 8
-
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-08-23
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data