ABCA7 Antibody

• Catalog number
  bs-11180R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ABCA7 Primary Polyclonal Antibody
• Also known as
  ABCA7 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ABCA7
• Specificity
  This is a highly specific antibody against ABCA7.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ABCA7
• Tested Applications
  FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ABC transporter ABCA7; ABC transporter member 7; ABCA SSN; ABCX; ATP binding cassette sub family A ABC1 member 7; ATP binding cassette sub family A member 7; ATP binding Cassette Transporter A7;,FLJ40025; Macrophage ABC transporter; ABCA7_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ABCA7  
• Gene symbol
  ABCA7
• Short name
  Anti-ABCA7
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ABCA7 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  ATP-binding cassette, sub-family A (ABC1), member 7, ABCA-SSN and ABCX, ABCA7 and IDBG-13665 and ENSG00000064687 and 10347, apolipoprotein A-I receptor activity, Cell surfaces, Abca7 and IDBG-171979 and ENSMUSG00000035722 and 27403, ABCA7 and IDBG-645574 and ENSBTAG00000020766 and 511762

Gene info

• Identity
  HGNC:37
• Gene
  ABCA7
• Long gene name
  ATP binding cassette subfamily A member 7
• Synonyms gene name
  • ATP-binding cassette, sub-family A (ABC1), member 7
• Synonyms
  • ABCX
• GenBank acession
  • AF328787
• Locus
  19p13.3
• Discovery year
  1999-06-11
• Entrez gene record
  10347
• Pubmed identfication
  • 10873640
  • 11435699
  • 12917409
• RefSeq identity
  • NM_019112
• Classification
  • ATP binding cassette subfamily A
• VEGA ID
  OTTHUMG00000167547

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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