SLITRK2 Antibody, PE Conjugated

• Catalog number
  bs-11955R-PE
• Price
  Please ask
• Size
  0.1ml

• Long name
  SLITRK2 Polyclonal Antibody, PE Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  PE
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SLITRK2
• Specificity
  This is a highly specific antibody against SLITRK2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human SLITRK2
• Tested applications
  FCM
• Recommended dilutions
  FCM(1:20-100)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  480,565nm/578nm
• Synonyms
  CXorf2; KIAA1854; SLIK2_HUMAN; SLIT and NTRK like protein 2; SLIT and NTRK-like protein 2; SLITL1; SLITRK 2; Slitrk2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SLITRK2   Conjugated  
• Gene symbol
  SLITRK2
• Short name
  Anti-SLITRK2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  PE
• Alternative name
  Anti-SLITRK2 PAb PE
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13449
• Gene
  SLITRK2
• Long gene name
  SLIT and NTRK like family member 2
• Synonyms gene
  • SLITL1
  • TMEM257
  • CXorf1
• Synonyms gene name
  • slit-like 1 (Drosophila)
  • SLIT and NTRK-like family, member 2
  • transmembrane protein 257
  • chromosome X open reading frame 1
• Synonyms
  • KIAA1854
  • CXorf2
• GenBank acession
  • Y19205
• Locus
  Xq27.3
• Discovery year
  2004-03-11
• Entrez gene record
  84631
• Pubmed identfication
  • 11347906
  • 14557068
• RefSeq identity
  • NM_032539
• Classification
  • SLIT and NTRK like family
• VEGA ID
  OTTHUMG00000022595
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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