PSF2 Antibody, FITC Conjugated

• Catalog number
  bs-7824R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  PSF2 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PSF2
• Specificity
  This is a highly specific antibody against PSF2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human PSF2
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The GINS complex is composed of four subunits, encoded by SLD5, PSF1, PSF2, and PSF3. In S. cerevisiae, it was first identified by genetic and biochemical methods to determine factors interacting with Sld5p. Genetic interactions between these four genes also suggest that they act together. The GINS complex was independently isolated in a large scale screen for cell cycle defects. A similar complex is found in Xenopus and has a ring-like structure. In yeast, all four genes are essential and cells defective in SLD5, PSF1, or PSF2 are impaired in their ability to replicate DNA. The complex localizes to origins of DNA replication and Sld5p was previously implicated as functioning in DNA replication due to its genetic interaction with DPB11. Additional genetic and biochemical interactions of the GINS complex with Dpb11p, Dpb2p, and Sld3p suggest that it functions in some way at the replication fork during DNA synthesis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  GINS complex subunit 2; GINS2; HSPC037; PSF2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  PSF2   Conjugated  
• Gene symbol
  GINS2, TAP2
• Short name
  Anti-PSF2
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-PSF2 PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:24575
• Gene
  GINS2
• Long gene name
  GINS complex subunit 2
• Synonyms gene name
  • GINS complex subunit 2 (Psf2 homolog)
• Synonyms
  • PSF2
  • Pfs2
• GenBank acession
  • BC003186
• Locus
  16q24.1
• Discovery year
  2006-05-04
• Entrez gene record
  51659
• Pubmed identfication
  • 11042152
  • 10810093
• RefSeq identity
  • NM_016095
• Classification
  • GINS complex
• VEGA ID
  OTTHUMG00000137646

Gene info

• Identity
  HGNC:44
• Gene
  TAP2
• Long gene name
  transporter 2, ATP binding cassette subfamily B member
• Synonyms gene
  • ABCB3
• Synonyms gene name
  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
• Synonyms
  • PSF2
  • RING11
  • D6S217E
• GenBank acession
  • M74447
• Locus
  6p21.32
• Discovery year
  1992-06-25
• Entrez gene record
  6891
• Pubmed identfication
  • 1529427
  • 1946428
  • 16395595
• RefSeq identity
  • NM_000544
• Classification
  • ATP binding cassette subfamily B
• VEGA ID
  OTTHUMG00000031068
• Locus Specific Databases
  • TAP2base: Mutation registry for TAP2 deficiency
  • IMGT/HLA Database
  • LRG_167

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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