c-Jun(Thr91+Thr93) Antibody, Cy5.5 Conjugated
Catalog number
bs-4601R-Cy5.5
Supplier
Price
387.32 USD
Size
0.1ml
Long name
c-Jun(Thr91+Thr93) Polyclonal Antibody, Cy5.5 Conjugated
Category
Conjugated Primary Antibodies
Conjugation
Cy5.5
Host Organism
Rabbit (Oryctolagus cuniculus)
Target Antigen
c-Jun Thr91+Thr93
Specificity
This is a highly specific antibody against c-Jun Thr91+Thr93.
Modification
Phosphorylation
Modification site
Thr91+Thr93
Clonality
Polyclonal
Clone
Polyclonal antibody
Concentration
1ug per 1ul
Source
KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of (Thr91+Thr93)
Gene ID number
3725
Tested applications
IF(IHC-P)
Recommended dilutions
IF(IHC-P)(1:50-200)
Crossreactivity
Human, Mouse, Rat
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen background
C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation Emission
675nm/694nm
Synonyms
p-c-JunThr91+Thr93; c-Jun phospho Thr91+Thr93; c-Jun phospho T91+T93; p-c-Jun Thr93; Jun oncogene; JUN; Activator Protein 1; AP 1; AP1; AP-1; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN protein; JUNC; p39; Proto oncogene cJun; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; JUN_HUMAN; Transcription factor AP-1; Activator 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog.
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
Additional conjugation
Cy5.5, Cy5.5
Conjugated
These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
French translation
anticorps
Gene target
Short name
Anti-c-Jun Thr91+Thr93
Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
Isotype
Immunoglobulin G (IgG)
Label
Cy5.5
Alternative name
Anti-c-Jun Thr91+Thr93 PAb Cy5.5
Alternative technique
antibodies
Alternative to gene target
jun proto-oncogene, AP-1 and AP1 and c-Jun, JUN and IDBG-99221 and ENSG00000177606 and 3725, HMG box domain binding, nuclei, Jun and IDBG-164161 and ENSMUSG00000052684 and 16476, JUN and IDBG-638846 and ENSBTAG00000004037 and 280831
MeSH Data
Name
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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