MyD88 Antibody, ALEXA FLUOR 647

  • Catalog number
    bs-1047R-A647
  • Price
    Please ask
  • Size
    100ul
  • Long name
    MyD88 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
  • Also known as
    Anti-MyD88 PAb ALEXA FLUOR 647
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 647
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    MyD88
  • Specificity
    This is a highly specific antibody against MyD88.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    240-290/296
  • Subcellular location
    Cytoplasm
  • Source
    KLH conjugated synthetic peptide derived from mouse MyD88
  • Gene ID Number
    17874
  • Swiss Prot
    P22366
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS). Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    650nm/665nm
  • Synonyms
    Myeloid differentiation primary response protein MyD88; Myd88
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-MyD88 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 647
  • French translation
    anticorps
  • Gene target
    MyD88  
  • Gene symbol
    MYD88, TIRAP, MAL
  • Short name
    Anti-MyD88
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 647
  • Alternative name
    MyD88 Polyclonal Antibody, ALEXA FLUOR 647
  • Alternative technique
    antibodies
  • Alternative to gene target
    myeloid differentiation primary response 88, MYD88D, MYD88 and IDBG-25713 and ENSG00000172936 and 4615, TIR domain binding, Plasma membranes, Myd88 and IDBG-204565 and ENSMUSG00000032508 and 17874, MYD88 and IDBG-644299 and ENSBTAG00000000563 and 444881
Gene info
  • Identity
  • Gene
  • Long gene name
    MYD88 innate immune signal transduction adaptor
  • Synonyms gene name
    • myeloid differentiation primary response gene (88)
    • myeloid differentiation primary response 88
  • GenBank acession
  • Locus
  • Discovery year
    1997-12-23
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • TIR domain containing
    • My-T-BRC complex
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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