MBP Antibody, ALEXA FLUOR 647

• Catalog number
  bs-0380R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  MBP Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-MBP PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MBP
• Specificity
  This is a highly specific antibody against MBP.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  45-87/167
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from Guinea Pig MBP
• Tested applications
  IF(IHC-P), IF(IHC-F)
• Recommended dilutions
  IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  MBP_CAVPO;Myelin Basic Protein; Myelin basic protien; GDB; Golli MBP; Hemopoietic MBP; HMBPR; HUGO; MBP; MGC99675; MLD; Myelin A1 Protein; Myelin Deficient; Myelin Membrane Encephalitogenic Protein; SHI; Shiverer; SP
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-MBP exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  MBP  
• Gene symbol
  MBP, PRG2, ENO1, HIVEP2, HIVEP1
• Short name
  Anti-MBP
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  mbp
• Alternative name
  MBP Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6925
• Gene
  MBP
• Long gene name
  myelin basic protein
• Locus
  18q23
• Discovery year
  1986-01-01
• Entrez gene record
  4155
• Pubmed identfication
  • 2425357
• RefSeq identity
  • NM_001025081
• VEGA ID
  OTTHUMG00000132874

Gene info

• Identity
  HGNC:9362
• Gene
  PRG2
• Long gene name
  proteoglycan 2, pro eosinophil major basic protein
• Synonyms gene name
  • proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
• Synonyms
  • MBP
  • BMPG
  • proMBP
• Synonyms name
  • eosinophil major basic protein
• GenBank acession
  • BC005929
• Locus
  11q12.1
• Discovery year
  1993-09-29
• Entrez gene record
  5553
• Pubmed identfication
  • 1565101
• RefSeq identity
  • NM_002728
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000167027

Gene info

• Identity
  HGNC:3350
• Gene
  ENO1
• Long gene name
  enolase 1
• Synonyms gene
  • ENO1L1
  • MPB1
• Synonyms gene name
  • enolase 1, (alpha)
• Synonyms
  • PPH
  • MBP-1
• Synonyms name
  • alpha-enolase
• GenBank acession
  • BC022545
• Locus
  1p36.23
• Discovery year
  1989-04-21
• Entrez gene record
  2023
• Pubmed identfication
  • 9653645
  • 9691177
• RefSeq identity
  • NM_001428
• Classification
  • Enolases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000001773
• Locus Specific Databases
  • LRG_1165

Gene info

• Identity
  HGNC:4921
• Gene
  HIVEP2
• Long gene name
  HIVEP zinc finger 2
• Synonyms gene name
  • human immunodeficiency virus type I enhancer-binding protein 2
  • human immunodeficiency virus type I enhancer binding protein 2
• Synonyms
  • MBP-2
  • HIV-EP2
  • MIBP1
  • ZAS2
  • Schnurri-2
  • ZNF40B
• Synonyms name
  • c-myc intron binding protein 1
• GenBank acession
  • M60119
• Locus
  6q24.2
• Discovery year
  1992-10-21
• Entrez gene record
  3097
• Pubmed identfication
  • 1733857
  • 2022670
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000015713

Gene info

• Identity
  HGNC:4920
• Gene
  HIVEP1
• Long gene name
  HIVEP zinc finger 1
• Synonyms gene
  • ZNF40
• Synonyms gene name
  • human immunodeficiency virus type I enhancer-binding protein 1
  • zinc finger protein 40
  • human immunodeficiency virus type I enhancer binding protein 1
• Synonyms
  • CIRIP
  • MBP-1
  • CRYBP1
  • PRDII-BF1
  • ZAS1
  • Schnurri-1
  • ZNF40A
• GenBank acession
  • J05011
• Locus
  6p24.1
• Discovery year
  1990-10-04
• Entrez gene record
  3096
• Pubmed identfication
  • 2108316
  • 2037300
  • 2504707
• RefSeq identity
  • NM_002114
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000014265

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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