Glutathione S Transferase alpha Antibody, ALEXA FLUOR 350
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Catalog numberbs-13398R-A350
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PricePlease ask
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Size100ul
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Long nameGlutathione S Transferase alpha Antibody, ALEXA FLUOR 350 Conjugated
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Also known asAnti-GSTA1/Glutathione S Transferase alpha PAb ALEXA FLUOR 350
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 350
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenGSTA1/Glutathione S Transferase alpha
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SpecificityThis is a highly specific antibody against GSTA1/Glutathione S Transferase alpha.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GSTA1/Glutathione S Transferase alpha
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Gene ID Number2938
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenMembers of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. GSTs are differentially expressed in lung, liver and kidney tissue. Three isoforms, GSTA1-1, GSTA1-4 and GSTM1, localize to the mitochondria in addition to the cytoplasm. In normal and transformed cells, the oncoprotein Myb transcriptionally upregulates GSTM1. This isoform shows high specific activity for aflatoxin B1 epoxide conjugation, suggesting an important role for this interaction in the defense against both chemical and oxidative stress. The C-terminal domain of GSTA1 may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission343nm/442nm
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SynonymsGlutathione S alkyltransferase A1; Glutathione S aralkyltransferase A1; Glutathione S aryltransferase A1; Glutathione S transferase 2; Glutathione S transferase A1; Glutathione S transferase alpha 1; Glutathione S transferase Ha subunit 1; Glutathione S-transferase A1; GST 2; GST class alpha; GST class alpha 1; GST class alpha member 1; GST class-alpha member 1; GST epsilon; GST HA subunit 1; GST, class alpha, 1; GST-epsilon; GST2; GSTA 1; GSTA1 1; GSTA1; GSTA1 protein; GSTA1-1; GSTA1_HUMAN; GTH 1; GTH1; HA subunit 1; MGC131939; OTTHUMP00000016611; S hydroxyalkylglutathione lyase A1.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 350
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DescriptionThe Anti-GSTA1/Glutathione S Transferase alpha is a α- or alpha protein sometimes glycoprotein present in blood.
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French translationanticorps
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Gene target
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Gene symbolGSTA5, GSTA1, GSTA3
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Short nameAnti-GSTA1/Glutathione S Transferase alpha
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 350
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Alternative nameGlutathione S Transferase alpha Antibody, ALEXA FLUOR 350
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameglutathione S-transferase alpha 5
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Synonyms gene name
- glutathione S-transferase A5
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GenBank acession
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Locus
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Discovery year2002-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Soluble glutathione S-transferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglutathione S-transferase alpha 1
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Synonyms gene name
- glutathione S-transferase A1
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Locus
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Discovery year1991-12-06
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Entrez gene record
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Pubmed identfication
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Classification
- Soluble glutathione S-transferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglutathione S-transferase alpha 3
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Synonyms gene name
- glutathione S-transferase A3
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GenBank acession
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Locus
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Discovery year1994-04-29
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Entrez gene record
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Pubmed identfication
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Classification
- Soluble glutathione S-transferases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data