Coxsackie Adenovirus Receptor Antibody, ALEXA FLUOR 350

• Catalog number
  bs-2389R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  Coxsackie Adenovirus Receptor Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-Coxsackie Adenovirus Receptor PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Coxsackie Adenovirus Receptor
• Specificity
  This is a highly specific antibody against Coxsackie Adenovirus Receptor.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  20-70/365
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor
• Gene ID Number
  1525
• Swiss Prot
  P78310
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  CAR; HCAR; CAR4/6; Coxsackievirus and adenovirus receptor; CVB3-binding protein; Coxsackievirus B-adenovirus receptor; HCVADR; CXADR
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Coxsackie   Adenovirus   Receptor  
• Gene symbol
  CXADRP3, CXADRP2, CXADRP1
• Short name
  Anti-Coxsackie Adenovirus Receptor
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  Coxsackie Adenovirus Receptor Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies
• Virus
  adenovirus, coxsackie

Gene info

• Identity
  HGNC:33974
• Gene
  CXADRP3
• Long gene name
  CXADR pseudogene 3
• Synonyms gene name
  • coxsackie virus and adenovirus receptor pseudogene 3
• Locus
  18p11.21
• Discovery year
  2008-01-31
• Entrez gene record
  440224
• RefSeq identity
  • NR_024076
• VEGA ID
  OTTHUMG00000178700

Gene info

• Identity
  HGNC:33973
• Gene
  CXADRP2
• Long gene name
  CXADR pseudogene 2
• Synonyms gene name
  • coxsackie virus and adenovirus receptor pseudogene 2
• Locus
  15q11.2
• Discovery year
  2008-01-31
• Entrez gene record
  646243
• VEGA ID
  OTTHUMG00000171728

Gene info

• Identity
  HGNC:23770
• Gene
  CXADRP1
• Long gene name
  CXADR pseudogene 1
• Synonyms gene name
  • coxsackie virus and adenovirus receptor pseudogene 1
• Synonyms
  • CAR
  • CXADRP
• Locus
  21q11.2
• Discovery year
  2008-01-31
• Entrez gene record
  653108
• VEGA ID
  OTTHUMG00000074204

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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