CDKN1A (Thr57) Antibody, ALEXA FLUOR 647

• Catalog number
  bs-5238R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  CDKN1A (Thr57) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-CDKN1A Thr57 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CDKN1A Thr57
• Specificity
  This is a highly specific antibody against CDKN1A Thr57.
• Modification
  Phosphorylation
• Modification Site
  Thr57
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  30-70/164
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr57 [TE(p-T)PL]
• Gene ID Number
  1026
• Swiss Prot
  P38936
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; CDKN1A; MDA6; PIC1
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-CDKN1A Thr57 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  CDKN1A   Thr57  
• Gene symbol
  CDKN1A-AS1, CDKN1A
• Short name
  Anti-CDKN1A Thr57
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  CDKN1A (Thr57) Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  cyclin-dependent kinase inhibitor 1A (p21, Cip1), CAP20 and CDKN1 and CIP1 and MDA-6 and P21 and p21CIP1 and SDI1 and WAF1, CDKN1A and IDBG-85033 and ENSG00000124762 and 1026, metal ion binding, nuclei, Cdkn1a and IDBG-159848 and ENSMUSG00000023067 and 12575, CDKN1A and IDBG-630156 and ENSBTAG00000008353 and 513497

Gene info

• Identity
  HGNC:42399
• Gene
  CDKN1A-AS1
• Long gene name
  CDKN1A antisense RNA 1
• Synonyms gene name
  • CDKN1A antisense RNA 1 (non-protein coding)
• Synonyms
  • p21NAT
• GenBank acession
  • BX332409
• Locus
  6p21.1
• Discovery year
  2011-07-11
• Entrez gene record
  100861512
• Pubmed identfication
  • 19008947
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:1784
• Gene
  CDKN1A
• Long gene name
  cyclin dependent kinase inhibitor 1A
• Synonyms gene
  • CDKN1
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
• Synonyms
  • P21
  • CIP1
  • WAF1
  • SDI1
  • CAP20
  • p21CIP1
  • p21Cip1/Waf1
  • p21
• GenBank acession
  • U03106
• Locus
  6p21.2
• Discovery year
  1994-05-24
• Entrez gene record
  1026
• RefSeq identity
  • NM_078467
• VEGA ID
  OTTHUMG00000014603

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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