ADAMTS8 Antibody, ALEXA FLUOR 594

  • Catalog number
    bs-5859R-A594
  • Price
    Please ask
  • Size
    100ul
  • Long name
    ADAMTS8 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
  • Also known as
    Anti-ADAMTS8 PAb ALEXA FLUOR 594
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 594
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    ADAMTS8
  • Specificity
    This is a highly specific antibody against ADAMTS8.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAMTS8
  • Gene ID Number
    11095
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    590nm/617nm
  • Synonyms
    A disintegrin and metalloproteinase with thrombospondin mots 8; ADAMTS 8; METH 2; METH 8; METH8; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot 8; A disintegrin like and metalloprotease with thrombospondin type 1 mot 8; ADAM metallopeptidase with thrombospondin type 1 mot 8; ADAM TS 8; ADAM TS8; METH2; ATS8_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • French translation
    anticorps
  • Gene target
    ADAMTS8  
  • Gene symbol
    ADAMTS8
  • Short name
    Anti-ADAMTS8
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    ADAMTS8 Polyclonal Antibody, ALEXA FLUOR 594
  • Alternative technique
    antibodies
  • Alternative to gene target
    ADAM metallopeptidase with thrombospondin type 1 motif, 8, ADAM-TS8 and METH2, ADAMTS8 and IDBG-76259 and ENSG00000134917 and 11095, low affinity phosphate transmembrane transporter activity, Extracellular, Adamts8 and IDBG-146397 and ENSMUSG00000031994 and 30806, ADAMTS8 and IDBG-642991 and ENSBTAG00000010411 and 512544
Gene info
  • Identity
  • Gene
  • Long gene name
    ADAM metallopeptidase with thrombospondin type 1 motif 8
  • Synonyms gene name
    • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1999-08-23
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • ADAM metallopeptidases with thrombospondin type 1 motif
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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