Recombinant Human Growth hormone receptor (GHR), partial
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Catalog numberRPC20477-50ug
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Price:
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Size50ug
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Estimated Turnaround Time6-11 business days
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Gene NameGHR
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Alternative NamesSomatotropin receptor
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SourceE.coli
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Purity> 90% by SDS-PAGE
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Shipping ConditionsIce packs
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Storage conditionsShort term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
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Shelf life12 months in lyophilized form; 6 months in solution form.
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RestrictionFor research use only. Not for diagnostic procedures.
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DescriptionHormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolGHR
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Short nameRecombinant Growth hormone receptor (GHR), partial
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHomo sapiens (Human), Humans
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Alternative nameRec. H. sapiens Growth hormone receptor (growth hormone receptor), partial
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Alternative techniquerec
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Alternative to gene targetgrowth hormone receptor, GHBP, GHR and IDBG-18930 and ENSG00000112964 and 2690, proline-rich region binding, nuclei, Ghr and IDBG-127871 and ENSMUSG00000055737 and 14600, GHR and IDBG-629685 and ENSBTAG00000001335 and 280805
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Gene info
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Identity
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Gene
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Long gene namegrowth hormone receptor
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Synonyms
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Synonyms name
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Locus
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Discovery year1989-06-30
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Entrez gene record
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RefSeq identity
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Classification
- Fibronectin type III domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data