Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)

• Catalog number
  RPU52109
• Price
  Please ask
• Size
  500 μg

• Verified reactivity
  Homo sapiens (Human)
• Protein number
  Q9Y6Q6
• Gene number
  Please refer to GenBank
• Other name
  CD265; TNFRSF11A; TNFRSF11-A; ODFR; OFE; TRANCER; Osteoclast differentiation factor receptor; Tumor Necrosis Factor Receptor Superfamily,Member 11a,NFKB Activator
• Protein origin
  E.coli
• Protein region
  Please contact us.
• Protein sequence
  Please contact us.
• Information about sequence
  Val330~Lys615
• Expected molecular weight
  33.9kDa
• Protein purity
  ≥ 98%
• Verified applications
  SDS-PAGE; WB; ELISA; IP.
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  7-11 business days
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Receptor   Activator   Factor   Kappa   RANk  
• Gene symbol
  TNFRSF11A
• Short name
  Recombinant Receptor Activator Of Factor Kappa B (RANk)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Label
  two N-terminal Tags, His-tag and T7-tag
• Alternative name
  Rec. Receptor Activator on Nuclear Factor Kappa B (RANk)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:11908
• Gene
  TNFRSF11A
• Long gene name
  TNF receptor superfamily member 11a
• Synonyms gene
  • PDB2
  • LOH18CR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 11a, activator of NFKB
  • Paget disease of bone 2
  • loss of heterozygosity, 18, chromosomal region 1
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator
• Synonyms
  • RANK
  • CD265
  • FEO
  • ODFR
  • TRANCE-R
• Synonyms name
  • osteoclast differentiation factor receptor
  • receptor activator of nuclear factor kappa B
  • familial expansile osteolysis
  • TRANCE receptor
• GenBank acession
  • AF018253
• Locus
  18q21.33
• Discovery year
  1998-12-04
• Entrez gene record
  8792
• Pubmed identfication
  • 9367155
  • 10615125
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000132779
• Locus Specific Databases
  • LRG_194

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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