Human IGF-II (RECOMBINANT)

• Catalog number
  GF-060-8
• Price
  Please ask
• Size
  500µg

• Product type
  Growth Factors/Cytokines/Enzymes
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  -
• Gene symbol
  F2, MT-CSB2, APOL2
• Short name
  IGF-II (RECOMBINANT)
• Technique
  Recombinant, IGF, igfs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Austral Biologicals advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  H. sapiens IGF-II (Rec.)
• Alternative technique
  rec, igfs

Gene info

• Identity
  HGNC:3535
• Gene
  F2
• Long gene name
  coagulation factor II, thrombin
• Synonyms gene name
  • coagulation factor II (thrombin)
• Synonyms name
  • prepro-coagulation factor II
• GenBank acession
  • M33031
• Locus
  11p11.2
• Discovery year
  2001-06-22
• Entrez gene record
  2147
• Classification
  • Receptor ligands
  • Gla domain containing
  • Complement system regulators and receptors
• VEGA ID
  OTTHUMG00000150344
• Locus Specific Databases
  • LRG_551

Gene info

• Identity
  HGNC:7425
• Gene
  MT-CSB2
• Long gene name
  mitochondrially encoded conserved sequence block II
• Synonyms gene
  • MTCSB2
• Synonyms gene name
  • conserved sequence block II
• Synonyms
  • CSB-II
• Locus
  mitochondria
• Discovery year
  1989-10-11
• Pubmed identfication
  • 2982153
• Classification
  • Mitochondrially encoded regions

Gene info

• Identity
  HGNC:619
• Gene
  APOL2
• Long gene name
  apolipoprotein L2
• Synonyms
  • APOL-II
• Synonyms name
  • apolipoprotein L-II
• GenBank acession
  • AF324224
• Locus
  22q12.3
• Discovery year
  1999-10-29
• Entrez gene record
  23780
• Pubmed identfication
  • 10591208
  • 11374903
• RefSeq identity
  • NM_145637
• Classification
  • Apolipoproteins
• VEGA ID
  OTTHUMG00000150634

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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