TSH (beta), thyroid stimulating hormone receptor

  • Catalog number
    AS10 1361
  • Price
    Please ask
  • Size
    1 mg
  • Available ordering format
    Liquid
  • Immunogen
    human TSH (intact) AAR07906
  • Raised in
    Sheep
  • Clonality
    Polyclonal
  • Clone
    Polyclonal
  • Purification
    Affinity purified
  • How to reconstitute
    See included datasheet or contact our support service
  • Storage condition
    2-8 °C.
  • Verified applications
    This antibody is suitable for all immunoassay applications
  • Connected products
    This antibody pairs with: AS10 1315 | TSH (beta) | thyroid stimulating hormone receptoranti-sheep secondary antibodies
  • Recommended dilutions for use
    The optimal working dilution should be determined by the investigator.
  • Molecular weight expected аpparent
    see datasheet
  • Verified reactivity
    human TSH (intact), human TSH (beta)
  • Possible reactivity
    n.a.
  • No reactivity
    no confirmed exceptions from predicted reactivity known in the moment
  • Supplementary information
    Affinity purified using solid phase human Thryoid Stimulating Hormone (TSH, intact). Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0).Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preservative. Antibody purity is > 95% based on SDS-PAGE.
  • References
    to be added when available
  • Scientific context
    TSH protein can be found in normal human thyroid glands. It responds to thyroid-stymulating hormone (thyrotopin).
  • Notes
    This antibody has been cross absorbed to remove antibodies to TSH (alpha)
  • Protein number
    Refer to NCBI
  • TAIR number
    Refer to NCBI
  • Description
    Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
  • Short name
    TSH (beta), thyroid stimulating hormone receptor
  • Alternative name
    TSH (b), thyroid stimulating hormone receptor
  • Tissue
    thyroid
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