FGF2, Basic fibroblast growth factor
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Catalog numberIMS01-138-313
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PricePlease ask
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Size100 µl (13 mg/ml)
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Available ordering formatLiquid in 0.9 % NaCl, 0.1 % sodium azide
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Immunogenpurified full length native protein P09038
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Raised inHen
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ClonalityPolyclonal
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ClonePolyclonal
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PurificationTotal IgY fraction
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How to reconstituteSee included datasheet or contact our support service
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Storage conditionstore at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
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Verified applicationsWestern blot (WB)
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Connected productsno related to other products
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Recommended dilutions for use1: 1000 with standard ECL (WB), 1: 1000 (ELISA)
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Molecular weight expected аpparent18 kDa
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Verified reactivityhuman
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Possible reactivitybovine, chicken, mouse, rat, sheep
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No reactivityno confirmed exceptions from predicted reactivity known in the moment
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Supplementary informationreacts with human recombinant FGF2. No reactivity with other human serum proteins
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Referencesto be added when available
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Scientific contextBasic Fibroblast Growth Factor (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
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Notesthe IgY fraction is isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation
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Protein numberP09038
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TAIR numberRefer to NCBI
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DescriptionBasic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Gene target
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Gene symbolFGF2, FGF13
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Short nameFGF2, fibroblast growth factor
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Alternative namefibroblast growth factor 2 (basic), Basic fibroblast growth factor
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Alternative to gene targetfibroblast growth factor 2 (basic), BFGF and FGF-2 and FGFB and HBGF-2, FGF2 and IDBG-37039 and ENSG00000138685 and 2247, chemoattractant activity, nuclei, Fgf2 and IDBG-140464 and ENSMUSG00000037225 and 14173, BT.66957 and IDBG-630303 and ENSBTAG00000005691 and 281161
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Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 2
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Synonyms gene
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Synonyms gene name
- fibroblast growth factor 2 (basic)
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
- Receptor ligands
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 13
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Synonyms gene
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Synonyms gene name
- long intergenic non-protein coding RNA 889
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-12-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
- MicroRNA protein coding host genes
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VEGA ID