Thyroid Transcription Factor-1 (TTF-1), Clone: SPT24, Mouse Monoclonal antibody-Human; frozen/paraffin, IH/WB
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Catalog numberMEDCLA678-1
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PricePlease ask
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Size1000ul
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Alternative name 1Thyroid Transcription Factor-1 (TTF-1), Clone: SPT24, Mab anti-Human; frozen/paraffin, IH/WB
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Alternative name 2Thyroid Transcription Factor-1 (TTF-1), Clone: SPT24, Mab antibody-Human; frozen/paraffin, IH/WB
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Alternative name 3Thyroid Transcription Factor-1 (TTF-1), Clone: SPT24, Mab antibody-Homo sapiens; frozen/paraffin, IH/WB
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Alternative name 4anti-Thyroid Transcription Factor-1 TTF-1 Clone: SPT24
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Alternative name 5Thyroid Transcription Factor-1 TTF-1 Clone: SPT24
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ClonalityMonoclonal Antibody
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DescriptionThis is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.
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Storage and handlingGenerally, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for longer periods - at -20 . Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°C.
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AdvisoryTo keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by accurate-monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional descriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolNKX2-1, TTF1, RHOH, FOXE1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
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Short nameThyroid Transcription Factor-1 (TTF-1), Clone: SPT24, Mouse Monoclonal antibody- ; frozen/paraffin, IH/
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TechniqueMouse monoclonal, Antibody, paraffin, frozen, Mouse, WB, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals, Western Blot on a membrane
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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SpeciesHuman, Humans, Mouses
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Alternative nameThyroid Transcription Factor-1 (TTF-1), clonality: SPT24, Mouse monoclonal (antibody to-)-H. sapiens; -25°C frozen/paraffin, IH/Western Blot
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Alternative techniqueantibodies, murine
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Tissuefrozen, thyroid
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Gene info
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Identity
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Gene
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Long gene nameNK2 homeobox 1
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Synonyms gene
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Synonyms gene name
- benign chorea
- thyroid transcription factor 1
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Synonyms
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Locus
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Discovery year1992-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametranscription termination factor 1
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Synonyms gene name
- transcription termination factor, RNA polymerase I
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GenBank acession
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Locus
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Discovery year1996-05-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myb/SANT domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameras homolog family member H
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Synonyms gene
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Synonyms gene name
- ras homolog gene family, member H
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-04-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Rho family GTPases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameforkhead box E1
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Synonyms gene
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Synonyms gene name
- forkhead box E2
- forkhead box E1 (thyroid transcription factor 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-02-14
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Entrez gene record
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Pubmed identfication
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Classification
- Forkhead boxes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
MeSH Data
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Name
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ConceptScope note: Thinly cut sections of frozen tissue specimens prepared with a cryostat or freezing microtome.
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Tree numbers
- E01.370.225.500.620.530.160.260
- E01.370.225.750.600.530.160.260
- E05.200.500.620.530.160.260
- E05.200.750.600.530.160.260
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data