p15INK4b (Cyclin Dependent Kinase Inhibitor), 15kD, Clone: DCS-114, Mouse Monoclonal antibody-Human, NO X w/Mouse or Rat; IF/IP (native)
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Catalog numberBMDV10134
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Price:
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Size500ul
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Alternative name 1p15INK4b (Cyclin Dependent Kinase Inhibitor), 15kD, Clone: DCS-114, Mab anti-Human, NO X w/Mouse or Rat; IF/IP (native)
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Alternative name 2p15INK4b (Cyclin Dependent Kinase Inhibitor), 15kD, Clone: DCS-114, Mab antibody-Human, NO X w/Mouse or Rat; IF/IP (native)
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Alternative name 3p15INK4b (Cyclin Dependent Kinase Inhibitor), 15kD, Clone: DCS-114, Mab antibody-Homo sapiens, NO X w/Mus musculus or Rattus norvegicus; IF/IP (native)
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Alternative name 4anti-p15INK4b Cyclin De ndent Kinase Inhibitor 15kD Clone: DCS-114 NO X w/ or native
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Alternative name 5p15INK4b Cyclin De ndent Kinase Inhibitor 15kD Clone: DCS-114 NO X w/ or native
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ClonalityMonoclonal Antibody
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DescriptionThis is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.
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Storage and handlingGenerally, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for longer periods - at -20 . Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°C.
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AdvisoryTo keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by accurate-monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolREXO2, CDK5RAP3, OR4H6P
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Short namep15INK4b (Cyclin Dependent Kinase Inhibitor), 15kD, Clone: DCS-114, Mouse Monoclonal antibody- , NO X w/Mouse ; IF/IP (native)
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TechniqueMouse monoclonal, Antibody, Mouse, IF, IP, antibodies against human proteins, antibodies for, Immunoprecipitation, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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SpeciesRat, Humans, Mouses, Rats
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Alternative namep15INK4b (Cyclin Dependent phosphorylation catalyst suppressor), 15kD, clonality: DCS-114, Mouse monoclonal (antibody to-)-H. sapiens, NO X w/Mouse and Rat; IF/IP (native)
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameRNA exonuclease 2
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Synonyms gene name
- REX2, RNA exonuclease 2 homolog (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-08-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Exonucleases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCDK5 regulatory subunit associated protein 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 4 subfamily H member 6 pseudogene
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Synonyms gene
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Synonyms gene name
- olfactory receptor, family 4, subfamily H, member 8 pseudogene
- olfactory receptor, family 4, subfamily H, member 6 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-11-25
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Entrez gene record
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Pubmed identfication
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Classification
- Olfactory receptors, family 4
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data