PLC gamma 1(Tyr775) Antibody, FITC Conjugated
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Catalog number
bs-5546R-FITC
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Price
Please ask
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Size
0.1ml
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Long name
PLC gamma 1(Tyr775) Polyclonal Antibody, FITC Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
FITC
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
PLC gamma 1Tyr775
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Specificity
This is a highly specific antibody against PLC gamma 1Tyr775.
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Modification
Phosphorylation
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Modification site
Tyr775
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr775
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Gene ID number
5335
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
494nm/518nm
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Synonyms
PLCG1phospho Y775; PLC 1; PLC 148; PLC gamma 1; PLC II; PLC1; PLC148; PLCG 1; PLCG1; PLCgamma1; PLCII; triphosphoinositide phosphodiesterase; 1 phosphatidyl D myo inositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; phosphatidylinositol phospholipase C; phosphodiesterase gamma 1; phosphoinositidase C; phosphoinositide phospholipase C; Phospholipase C 148; phospholipase C gamma 1 formerly subtype 148; Phospholipase C gamma 1; phospholipase C-148; PLCG1_HUMAN.
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
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Additional conjugation
Anti-FITC Antibody
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French translation
anticorps
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Gene target
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Gene symbol
PLCB1, PLCL1, PLCG1, PLCH2, PDIA3
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Short name
Anti-PLC gamma 1Tyr775
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Technique
Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
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Isotype
Immunoglobulin G (IgG)
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Label
FITC
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Alternative name
Anti-PLC gamma 1Tyr775 PAb FITC
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Alternative technique
antibodies, fluorescine
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Gene info
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Identity
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Gene
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Long gene name
phospholipase C beta 1
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Synonyms gene name
- phospholipase C, beta 1 (phosphoinositide-specific)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-21
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
- C2 domain containing phospholipases
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
phospholipase C gamma 1
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Synonyms gene
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Synonyms gene name
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C, gamma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1989-05-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- MicroRNA protein coding host genes
- Phospholipases
- SH2 domain containing
- C2 domain containing phospholipases
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
phospholipase C eta 2
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Synonyms gene
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Synonyms gene name
- phospholipase C-like 4
- phospholipase C, eta 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2004-07-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
- Phospholipases
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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