Mouse Anti OVA Monoclonal IgG1 Antibogy L71, 1 mg, lyophilized

• Catalog number
  3008
• Price
  Please ask
• Size
  1 vial

• Tech file
• Data sheet
• References
  ELISA kits for collagen and chondrocytes more
• Other chondrocytes and synoviocytes
• References of collagen and chondrocyte research and assays
  Kim W.­U., Yoo W.­H., Won Park, Kang Y.­M., Kim S.­I., Park J.­H., Lee S.­S., Joo Y.­S, Min J.­  K., Hong Y.­S., Lee S.­H., Park S.­H., Cho C.­S., Kim H.­Y. IgG antibodies to type II collagen reflect inflammatory activity in patients with rheumatoid arthritis. Journal of Rheumatology, 2000; 27(3):575­581. Terato K., DeArmey D.A., Ye X.J., Griffiths M.M., Cremer M.A. The Mechanism of Autoantibody  Formation to Cartilage in Rheumatoid Arthritis: Possible Cross­Reaction of Antibodies to Dietary  Collagens with Autologous Type II Collagen. Clin Imm Immunopath, 1996; 79(2):142­154(13)  Terato K, Shimozuru Y, Katayama K, et al. Specificity of antibodies to type II collagen in rheumatoid arthritis. Arthritis Rheum 1990;33:1493­500. Clague RB, Moore LJ. IgG and IgM antibody to native type II collagen in rheumatoid serum and synovial fluid: evidence for the presence of collagen­anticollagen immune complexes in synovial fluid. Arthritis Rheum 1984;27:1370­7. Fujii K, Tsuji M, Kitamura A, Murota K. The diagnostic significance of anti­type II collagen antibody assay in rheumatoid arthritis. Int Orthop 1992;16:272­6.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  The term “freeze-dry” is a lay description for the process of lyophilization protein powder. It is the conversion of water from a frozen state to a gaseous state without going through a liquid state. Aliquoting with 25 mM HEPES-KOH, pH 7.2 and 1 mM DTT and 10% weight on volume glycerol is suitable for storage of the reconstituted powder. The freeze-dry process removes moisture from the cells of specimens while the specimens remain frozen. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Gene
  Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

• Gene target
  OVA   Monoclonal   IgG1   Antibogy   L71  
• Short name
  Mouse Anti OVA Monoclonal IgG1 Antibogy L71, 1 mg,
• Technique
  Mouse, anti, antibody to, Monoclonals or monoclonal antibodies, mouses
• Host
  mouse
• Isotype
  IgG1
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to OVA monoclonal IgG1 Antibogy L71, 1 mg, lyophilized
• Alternative technique
  murine, antibodies

MeSH Data

• Name
  Freeze Drying
• Concept
  Scope note: Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
• Tree numbers
  • E01.370.225.500.620.760.160.260
  • E01.370.225.750.600.760.160.260
  • E02.792.156.260
  • E05.200.500.620.760.160.260
  • E05.200.750.600.760.160.260
  • E05.760.156.260
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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