Recombinant Human MTSS1 Protein (aa1-250, His & MBP tag) 50µg
-
Catalog number
PKSH030739-50µg
-
Price
Please ask
-
Size
50µg
-
-
Synonym
MIM;MIMA;MIMB
-
Activity
NA
-
Sequence
Met 1-Ser 250
-
Fusion tag
N-His & MBP
-
Accession
EAW92073.1
-
Expressed Host
E. coli
-
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
-
Purity
＞80 % as determined by SDS-PAGE
-
Endotoxin
Please contact us for more information.
-
Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Mol Mass
71.8 kDa
-
AP Mol Mass
66 kDa
-
Formulation
Lyophilized from sterile PBS, pH 7.4
-
Reconstitution
Please refer to it for detailed information.
-
Background
MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor missing in metastatic bladder carcinoma cell lines. MTSS1 is a prognostic indicator of disease-free survival in breast cancer patients and demonstrates the ability to play a role in governing the metastatic nature of breast cancer cells. MTSS1 may serve as a useful biomarker for the prediction of outcome of gastric cancer. The down-regulation of MTSS1 that may be caused by DNA methylation was also observed in many other types of cancer.Recent work proposed that MIM also potentiates Sonic hedgehog (Shh)-induced gene expression. MTSS1 as a multiple functional molecular player and has an important role in development, carcinogenesis and metastasis.
-
-
-
Conjugation
histidine
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
MBP, PRG2, MTSS1, ENO1, HIVEP2, HIVEP1
-
Short name
Recombinant MTSS1 Protein (aa1-250, His & MBP tag) 50µg
-
Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
-
Label
His
-
Species
Human, Humans
-
Alternative name
Rec. H. sapiens metastasis suppressor 1 Protein (aa1-250, histidine & MBP detection labelled) 50µg
-
Alternative technique
rec
-
Alternative to gene target
metastasis suppressor 1, MIM and MIMA and MIMB, MTSS1 and IDBG-35101 and ENSG00000170873 and 9788, actin filament binding, Cell surfaces, Mtss1 and IDBG-143773 and ENSMUSG00000022353 and 211401, MTSS1 and IDBG-644178 and ENSBTAG00000020407 and 523498
-
Gene info
-
Identity
-
Gene
-
Long gene name
myelin basic protein
-
Locus
-
Discovery year
1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
enolase 1
-
Synonyms gene
-
Synonyms gene name
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1989-04-21
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Enolases
- MicroRNA protein coding host genes
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene name
HIVEP zinc finger 2
-
Synonyms gene name
- human immunodeficiency virus type I enhancer-binding protein 2
- human immunodeficiency virus type I enhancer binding protein 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1992-10-21
-
Entrez gene record
-
Pubmed identfication
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
HIVEP zinc finger 1
-
Synonyms gene
-
Synonyms gene name
- human immunodeficiency virus type I enhancer-binding protein 1
- zinc finger protein 40
- human immunodeficiency virus type I enhancer binding protein 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1990-10-04
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
