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NUMBL Antibody

NUMBL Antibody is available 1 time from Bioss primary unconjugated antibodies labs

bs-11974R | NUMBL Antibody size: 0.1ml | 318.83 USD

Catalog number bs-11974R
Price 318.83 USD
Size 0.1ml
1. Gene info
Identity 8061
Gene NUMBL
Long gene name NUMB like endocytic adaptor protein
Synonyms gene name
  • numb (Drosophila) homolog-like
Synonyms
  • NUMB-R
  • CTG3a
  • CAG3A
  • TNRC23
  • NUMBR
  • NUMBLIKE
GenBank acession
  • AF015401
Locus 19q13.2
Discovery year 1999-03-12
Entrez gene record 9253
Pubmed identfication
  • 9225980
  • 9303539
RefSeq identity
  • NM_004756
Classification
  • Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000182627
Product images
    #.png
Product files
Long name NUMBL Primary Polyclonal Antibody
Also known as NUMBL PAb
Category Primary Antibodies
Conjugation Unconjugated
Target Antigen NUMBL
Specificity This is a highly specific antibody against NUMBL.
Modification(s) None
Modification site(s) Unmodified antibody
Clonality Polyclonal antibody
Clone number Polyclonal antibody
Concentration 1ug per 1ul
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NUMBL
Tested Applications WB, IHC-P, IF(IHC-P)
Recommended dilutions WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity Human, Mouse, Rat
Cross reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen In Drosophila, neuronal cell fate decisions are directed by NUMB, a signaling adapter protein with two protein-protein interaction domains, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR). The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.
Purification method This antibody was purified via Protein A.
Storage conditions Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names CAG 3A; CAG3A; CTG 3a; CTG3a; NBL; NUMB Drosophilia Homolog Like; Numb homolog Drosophila like; Numb homolog like; Numb like protein; NUMB R; Numb-like protein; Numb-R; Numb-related protein; NUMBL; NUMBL_HUMAN; NUMBR; TNRC 23; TNRC23.
Properties If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetNUMBL
Short name Anti-NUMBL
Technique Antibody
Host Rabbit (Oryctolagus cuniculus)
Isotype Immunoglobulin G (IgG)
Alternative name NUMBL Polyclonal Antibody
Alternative technique antibodies
Alternative to gene target numb homolog (Drosophila)-like, CAG3A and CTG3a and NBL and NUMB-R and NUMBLIKE and NUMBR and TNRC23, NUMBL and IDBG-52025 and ENSG00000105245 and 9253, protein binding, Cytoplasm, Numbl and IDBG-160322 and ENSMUSG00000063160 and 18223, NUMBL and IDBG-638153 and ENSBTAG00000019461 and 510973
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Anti-NUMBL | Technique alternative | 01010306490
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