Orexin 2 Receptor Agonist
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Catalog number
B1124-5
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Price
Please ask
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Size
5 mg
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Alternative_name
4'-methoxy-N,N-dimethyl-3'-(N-(3-((2-(3-methylbenzamido)ethyl)amino)phenyl)sulfamoyl)-[1,1'-biphenyl]-3-carboxamide
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Description
Orexin-2 receptor agonist is a potent and selective selective nonpeptidic orexin2 receptor (OX2R) agonist (OX2R EC₅₀ = 0.023 μM).
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CAS Number
1796565-52-0
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₃₂H₃₄N₄O₅S
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Molecular Weight
586.22
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO (>5 mg/ml)
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Handling
Protect from air and light
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Tag Line
A selective nonpeptidic orexin 2 receptor (OX2R) agonist
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
36 months
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PubChem CID
91810287
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SMILES
CC1=CC=CC(=C1)C(=O)NCCNC2=CC(=CC=C2)NS(=O)(=O)C3=C(C=CC(=C3)C4=CC(=CC=C4)C(=O)N(C)C)OC
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InChi
1S/C32H34N4O5S/c1-22-8-5-10-25(18-22)31(37)34-17-16-33-27-12-7-13-28(21-27)35-42(39,40)30-20-24(14-15-29(30)41-4)23-9-6-11-26(19-23)32(38)36(2)3/h5-15,18-21,33,35H,16-17H2,1-4H3,(H,34,37)
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InChi Key
RHLMXWCISNJNDH-UHFFFAOYSA-N
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MSDS Available
Yes
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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