Kir, Low Endotoxin (KIR2D, Killer Cell Immunoglobulin (Ig)-like Receptor, CD158a, CD158b, P50.3) Antibody

• Catalog number
  GEN600318
• Price
  Please ask
• Size
  500ug

• Also known as
  Kir, Low Endotoxin
• Other names
  killer cell immunoglobulin-like receptor 3DL1; Killer cell immunoglobulin-like receptor 3DL1; killer cell immunoglobulin-like receptor 3DL1; NKAT-3; NK-receptor; KIR antigen 3DL1; killer Ig receptor; p70 NK receptor CL-2/CL-11; MHC class I NK cell receptor; CD158 antigen-like family member E; p70 killer cell inhibitory receptor; natural killer-associated transcript 3; HLA-BW4-specific inhibitory NK cell receptor; p70 natural killer cell receptor clones CL-2/CL-11; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1; CD158 antigen-like family member E; HLA-BW4-specific inhibitory NK cell receptor; MHC class I NK cell receptor; Natural killer-associated transcript 3; NKAT-3; p70 natural killer cell receptor clones CL-2/CL-11
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  KIR3DL1; KIR3DL1; KIR; NKB1; NKAT3; NKB1B; CD158E1; KIR3DL1/S1; CD158E; NKAT3; NKB1; NKAT-3
• Gene name synonims
  KIR3DL1; KIR3DL1; KIR; NKB1; NKAT3; NKB1B; CD158E1; KIR3DL1/S1; CD158E; NKAT3; NKB1; NKAT-3
• Other gene names
  KIR3DL1; KIR3DL1; KIR; NKB1; NKAT3; NKB1B; CD158E1; KIR3DL1/S1; CD158E; NKAT3; NKB1; NKAT-3
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  4j52
• Host organism
  Mouse (Mus musculus)
• Source organism
  Tissue culture supernatant
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family: CD158a, CD158b and P50.3. Specifically recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4). Reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2. No preservative added.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Kir   Endotoxin   KIR2D   Killer   Immunoglobulin   like   Receptor   CD158a   CD158b   P50  
• Gene symbol
  H3P40, CD40, NFKB1, ASCC1, ARHGEF7
• Short name
  Kir, Endotoxin (KIR2D, Killer Immunoglobulin (Ig)-like Receptor, CD158a, CD158b, P50 3) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-Kir, Low Endotoxin (KIR2D, Killer Cell Immunoglobulin (Ig)-like Receptor, CD158a, CD158b, P50.3)
• Alternative technique
  antibodies
• Tissue
  cell

Gene info

• Identity
  HGNC:54470
• Gene
  H3P40
• Long gene name
  H3 histone pseudogene 40
• Synonyms
  • p50
• Locus
  15q26.2
• Discovery year
  2019-08-02
• Entrez gene record
  115482723
• Pubmed identfication
  • 21782046
• RefSeq identity
  • NG_066067

Gene info

• Identity
  HGNC:11919
• Gene
  CD40
• Long gene name
  CD40 molecule
• Synonyms gene
  • TNFRSF5
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 5
  • CD40 molecule, TNF receptor superfamily member 5
• Synonyms
  • p50
  • Bp50
• GenBank acession
  • X60592
• Locus
  20q13.12
• Discovery year
  1993-08-27
• Entrez gene record
  958
• Pubmed identfication
  • 7687385
  • 2998589
• RefSeq identity
  • NM_001250
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000033053
• Locus Specific Databases
  • CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base)
  • LRG_40

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:24268
• Gene
  ASCC1
• Long gene name
  activating signal cointegrator 1 complex subunit 1
• Synonyms
  • CGI-18
  • ASC1p50
  • Em:AC022392.3
  • p50
• GenBank acession
  • AY013290
• Locus
  10q22.1
• Discovery year
  2004-03-17
• Entrez gene record
  51008
• Pubmed identfication
  • 10810093
  • 12077347
• RefSeq identity
  • NM_015947
• Classification
  • Activating signal cointegrator 1 complex
• VEGA ID
  OTTHUMG00000018434

Gene info

• Identity
  HGNC:15607
• Gene
  ARHGEF7
• Long gene name
  Rho guanine nucleotide exchange factor 7
• Synonyms gene name
  • Rho guanine nucleotide exchange factor (GEF) 7
• Synonyms
  • KIAA0142
  • PIXB
  • DKFZp761K1021
  • Nbla10314
  • DKFZp686C12170
  • BETA-PIX
  • COOL1
  • P85SPR
  • P85
  • P85COOL1
  • P50BP
  • PAK3
  • P50
• Synonyms name
  • SH3 domain-containing proline-rich protein
  • PAK-interacting exchange factor beta
• GenBank acession
  • D63476
• Locus
  13q34
• Discovery year
  2001-11-21
• Entrez gene record
  8874
• Pubmed identfication
  • 9207241
  • 9726964
• RefSeq identity
  • NM_001113511
• Classification
  • Pleckstrin homology domain containing
  • Dbl family Rho GEFs
• VEGA ID
  OTTHUMG00000017357

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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