DPPIV (Human) Antibody

• Catalog number
  6693-50
• Price
  Please ask
• Size
  50 μg

• Antibody Target
  DPPIV
• Target Alternative Name
  DPP4, DPP-4, ADABP, ADCP2, ADCP-2, CD26, CD-26, DPPIV, DPPIV, TP103, TP-103
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Mouse myeloma cell line NS0-derived recombinant human DPPIV/CD26
• Accession
  Q53TN1
• Gene Id
  1803
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  0.2 mg/ml in PBS
• Purification
  Antigen affinity purified
• Application
  Western Blot, IHC, ICC
• Positive Control
  Western Blot: Human PMBCs, IHC, ICC: Human PMBCs
• Application And Usages
  WB: 0.2 µg/ml, ICC: 5-15 µg/ml, IHC: 5-15 µg/ml
• Description
  Dipeptidyl peptidase-IV (DPPIV), also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• French translation
  anticorps

• Gene target
  DPPIV  
• Gene symbol
  FAP, DPP4
• Short name
  DPPIV ( ) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Goat IgG
• Species
  Human, Humans
• Alternative name
  DPPIV (H. sapiens) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3590
• Gene
  FAP
• Long gene name
  fibroblast activation protein alpha
• Synonyms gene name
  • fibroblast activation protein, alpha
• Synonyms
  • DPPIV
• Synonyms name
  • seprase
• GenBank acession
  • U09278
• Locus
  2q24.2
• Discovery year
  1995-03-28
• Entrez gene record
  2191
• Pubmed identfication
  • 9247085
  • 14707457
• Classification
  • DASH family
• VEGA ID
  OTTHUMG00000153890

Gene info

• Identity
  HGNC:3009
• Gene
  DPP4
• Long gene name
  dipeptidyl peptidase 4
• Synonyms gene
  • CD26
  • ADCP2
• Synonyms gene name
  • dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
  • adenosine deaminase complexing protein 2
  • dipeptidyl-peptidase 4
• Synonyms
  • DPPIV
• GenBank acession
  • M74777
• Locus
  2q24.2
• Discovery year
  1990-03-05
• Entrez gene record
  1803
• Pubmed identfication
  • 8101391
• Classification
  • CD molecules
  • DASH family
• VEGA ID
  OTTHUMG00000132056

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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