Stat3, phosphorylated (Ser727) (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF)

  • Catalog number
    MBS626628
  • Price
    Please ask
  • Size
    0.1 mL
  • Products_type
    Antibody
  • Products_short_name
    [Stat3]
  • Products_name_syn
    [Anti -Stat3, phosphorylated (Ser727) (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF)]
  • Other_names
    [signal transducer and activator of transcription 3 isoform 1; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3; DNA-binding protein APRF; acute-phase response factor; signal transducer and activator of transcription 3 (acute-phase response factor); Acute-phase response factor]
  • Other_gene_names
    [STAT3; STAT3; APRF; HIES; APRF]
  • Clonality
    Polyclonal
  • Reactivity
    Human, Mouse, Rat
  • Specificity
    Recognizes endogenous levels of mouse Stat3 only when phosphorylated at Ser727. Does not appreciably crossreact with the corresponding phospho-serines of other Stat proteins. Species Crossreactivity: Human and rat.
  • Purity
    Affinity Purified Purified by Protein A affinity chromatography.
  • Form
    Supplied as liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.
  • Storage_stability
    May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene target
  • Gene symbol
    STAT3
  • Short name
    Stat3, phosphorylated (Ser727) (Signal Transducer Activator of Transcription 3, Acute-phase Response Factor, APRF)
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    signal transducer and activator on transcription 3 (acute-phase response factor), phosphorylated (Ser727) (Signal Transducer and Activator on Transcription 3, Acute-phase Response Factor, APRF)
  • Alternative to gene target
    signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541
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