SMC2 Antibody

• Catalog number
  3754-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  SMC2
• Target Alternative Name
  SMC2, structural maintenance of chromosomes 2; SMC2L1, structural maintenance of chromosomes 2-like 1; CAPE, CAP-E, hCAP-E, human chromosome-associated protein E
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide of human SMC2
• Accession
  NP_006435.1
• Gene Id
  10592
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (1:500 – 1:2000). However, the optimal concentrations should be determined individually. HEK293T cell lysate can be used as a positive control.The antibody recognizes the SMC2 of human origin. Reactivity to other species has not been tested.
• Description
  Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SMC2  
• Gene symbol
  SMC2-DT, SMC2
• Short name
  SMC2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  SMC2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:50827
• Gene
  SMC2-DT
• Long gene name
  SMC2 divergent transcript
• Synonyms gene
  • SMC2-AS1
• Synonyms gene name
  • SMC2 antisense RNA 1 (head to head)
• Locus
  9q31.1
• Discovery year
  2014-06-25
• Entrez gene record
  101928550
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000185235

Gene info

• Identity
  HGNC:14011
• Gene
  SMC2
• Long gene name
  structural maintenance of chromosomes 2
• Synonyms gene
  • SMC2L1
• Synonyms gene name
  • SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
  • SMC2 structural maintenance of chromosomes 2-like 1 (yeast)
• Synonyms
  • hCAP-E
  • CAP-E
• GenBank acession
  • AF092563
• Locus
  9q31.1
• Discovery year
  2001-02-22
• Entrez gene record
  10592
• Pubmed identfication
  • 9789013
• Classification
  • Condensin I subunits
  • Condensin II subunits
  • Structural maintenance of chromosomes proteins
• VEGA ID
  OTTHUMG00000020401

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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