SIRT5 Antibody

• Catalog number
  bs-9456R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SIRT5 Primary Polyclonal Antibody
• Also known as
  SIRT5 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SIRT5
• Specificity
  This is a highly specific antibody against SIRT5.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  120-170/310
• Subcellular location
  Mitochondrion
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIRT5
• Gene ID number
  23408
• Swiss Prot
  Q9NXA8
• Tested Applications
  WB, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  SIR2L5; NAD-dependent protein deacylase sirtuin-5, mitochondrial; Regulatory protein SIR2 homolog 5; SIR2-like protein 5; SIRT5
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SIRT5  
• Gene symbol
  SIRT5
• Short name
  Anti-SIRT5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SIRT5 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14933
• Gene
  SIRT5
• Long gene name
  sirtuin 5
• Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 5
  • sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
• GenBank acession
  • AF083110
• Locus
  6p23
• Discovery year
  2001-03-20
• Entrez gene record
  23408
• Pubmed identfication
  • 10381378
• Classification
  • Sirtuins
• VEGA ID
  OTTHUMG00000014278

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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