BAY 59-3074

• Catalog number
  B1247-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  3-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl 4,4,4-trifluoro-1-butanesulfonic acid ester
• Description
  BAY 59-3074 is a partial agonist of CB1/CB2 receptor with Ki values of 48.3 nM and 45.5 nM for human CB1/CB2 receptors, respectively. It displays CB1 agonist activity in in vivo studies and displays anti-hyperalgesic and antiallodynic properties in rat models of chronic neuropathic and inflammatory pain.
• CAS Number
  406205-74-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₃F₆NO₄S
• Molecular Weight
  453.35
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO(>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A partial agonist of CB1/CB2 receptor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  10479060
• PubChem CID Link
• SMILES
  C1=CC(=CC(=C1)OS(=O)(=O)CCCC(F)(F)F)OC2=CC=CC(=C2C#N)C(F)(F)F
• InChi
  InChI=1S/C18H13F6NO4S/c19-17(20,21)8-3-9-30(26,27)29-13-5-1-4-12(10-13)28-16-7-2-6-15(14(16)11-25)18(22,23)24/h1-2,4-7,10H,3,8-9H2
• InChi Key
  LWUSZIVDPJPVBW-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BAY   59-3074  
• Gene symbol
  IGLVIV-59, IGHV4-59, MIR3074, CLIP3, RNU6-59P, HLA-J, LUC7L2, SNTB1, OR7A3P
• Short name
  BAY 59-3074
• Alternative name
  BAY 59-3074

Gene info

• Identity
  HGNC:5942
• Gene
  IGLVIV-59
• Long gene name
  immunoglobulin lambda variable (IV)-59 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (IV)-59
  • immunoglobulin lambda variable (IV)-59 pseudogene
• Synonyms
  • IGLV(IV)-59
• GenBank acession
  • D87000
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28761
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000150847

Gene info

• Identity
  HGNC:5654
• Gene
  IGHV4-59
• Long gene name
  immunoglobulin heavy variable 4-59
• GenBank acession
  • L10088
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28392
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151973

Gene info

• Identity
  HGNC:38268
• Gene
  MIR3074
• Long gene name
  microRNA 3074
• Synonyms
  • hsa-mir-3074
• Locus
  9q22.32
• Discovery year
  2010-04-30
• Entrez gene record
  100422842
• RefSeq identity
  • NR_036109
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:24314
• Gene
  CLIP3
• Long gene name
  CAP-Gly domain containing linker protein 3
• Synonyms gene name
  • CAP-GLY domain containing linker protein 3
• Synonyms
  • CLIPR-59
  • RSNL1
• Synonyms name
  • CLIP-170-related
  • restin-like 1
• GenBank acession
  • AJ427922
• Locus
  19q13.12
• Discovery year
  2007-01-04
• Entrez gene record
  25999
• Pubmed identfication
  • 11854307
• RefSeq identity
  • NM_015526
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000181747

Gene info

• Identity
  HGNC:42549
• Gene
  RNU6-59P
• Long gene name
  RNA, U6 small nuclear 59, pseudogene
• Synonyms gene
  • RNU6-59
• Synonyms gene name
  • RNA, U6 small nuclear 59
• Locus
  13q12.11
• Discovery year
  2011-08-08
• Entrez gene record
  100873767
• RefSeq identity
  • NR_046933

Gene info

• Identity
  HGNC:4967
• Gene
  HLA-J
• Long gene name
  major histocompatibility complex, class I, J (pseudogene)
• Synonyms gene
  • HLA-CDA12
  • D6S203
• Synonyms
  • CDA12
  • HLA-59
• GenBank acession
  • M80470
• Locus
  6p22.1
• Discovery year
  1992-06-25
• Entrez gene record
  3137
• Pubmed identfication
  • 1602142
• RefSeq identity
  • NR_024240
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031161
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:21608
• Gene
  LUC7L2
• Long gene name
  LUC7 like 2, pre-mRNA splicing factor
• Synonyms gene name
  • LUC7-like 2 (S. cerevisiae)
• Synonyms
  • CGI-74
  • CGI-59
  • H_NH0792N18.3
  • FLJ10657
  • LUC7B2
  • hLuc7B2
• Synonyms name
  • CGI-74 protein
• GenBank acession
  • AF151832
• Locus
  7q34
• Discovery year
  2003-07-15
• Entrez gene record
  51631
• Pubmed identfication
  • 17656373
• RefSeq identity
  • NM_016019
• VEGA ID
  OTTHUMG00000185163

Gene info

• Identity
  HGNC:11168
• Gene
  SNTB1
• Long gene name
  syntrophin beta 1
• Synonyms gene
  • SNT2B1
• Synonyms gene name
  • syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
• Synonyms
  • 59-DAP
  • A1B
  • BSYN2
  • TIP-43
  • SNT2
• Synonyms name
  • tax interaction protein 43
• GenBank acession
  • AF028828
• Locus
  8q24.12
• Discovery year
  1994-12-14
• Entrez gene record
  6641
• Pubmed identfication
  • 8183929
  • 9482110
• RefSeq identity
  • NM_021021
• Classification
  • PDZ domain containing
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000165041

Gene info

• Identity
  HGNC:8366
• Gene
  OR7A3P
• Long gene name
  olfactory receptor family 7 subfamily A member 3 pseudogene
• Synonyms gene
  • OR7A12P
  • OR7A14P
  • OR7A14
  • OR7A13P
• Synonyms gene name
  • olfactory receptor, family 7, subfamily A, member 3 pseudogene
• Synonyms
  • OR11-7b
  • OR19-12
  • OR14-59
  • OR14-11
• GenBank acession
  • AF065859
• Locus
  19p13.12
• Discovery year
  1998-11-09
• Entrez gene record
  26668
• Pubmed identfication
  • 9787077
• Classification
  • Olfactory receptors, family 7
• VEGA ID
  OTTHUMG00000183348

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