anti- ACHE antibody

• Catalog number
  FNab00083
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
• Immunogen
  acetylcholinesterase (Yt blood group)
• Synonyms
  Acetylcholinesterase, ACHE, ARACHE, N ACHE, YT
• Calculated MW
  71 kDa
• Uniprot ID
  P22303
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
• Image1
  Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab00083( ACHE Antibody) at dilution of 1:100
• Image4
  mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00083(ACHE antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ACHE  
• Gene symbol
  ACHE
• Short name
  anti- ACHE antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- acetylcholinesterase (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  acetylcholinesterase, ACEE and ARACHE and N-ACHE and YT, ACHE and IDBG-32513 and ENSG00000087085 and 43, protein self-association, nuclei, Ache and IDBG-204838 and ENSMUSG00000023328 and 11423, ACHE and IDBG-640435 and ENSBTAG00000001139 and 540446

Gene info

• Identity
  HGNC:108
• Gene
  ACHE
• Long gene name
  acetylcholinesterase (Cartwright blood group)
• Synonyms gene
  • YT
• Synonyms gene name
  • acetylcholinesterase (YT blood group)
  • acetylcholinesterase (Yt blood group)
• Synonyms name
  • Yt blood group
• Locus
  7q22.1
• Discovery year
  1989-06-02
• Entrez gene record
  43
• Pubmed identfication
  • 1380483
• RefSeq identity
  • NM_015831
• Classification
  • Blood group antigens
• VEGA ID
  OTTHUMG00000157033
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • LRG_804

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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