anti-JAG1 Antibody

• Catalog number
  8059
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate decisions (1). Ligands for Notch include JAG1, JAG2 and Delta. JAG1 is one of the DSL (Delta, Serrate, Lag2) transmembrane proteins that can activate Notch. It is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis (1,2). JAG1 is widely expressed in adult and fetal tissues and the mutation of the JAG1 gene is associated with Familial Tetrology of Fallot (3). JAG1 expression is associated with prostate cancer metastasis and is up-regulated in cervical squamous cell carcinoma (4,5).
• Gene names
  Jagged 1, AGS, AHD, AWS, CD339, HJ1, JAGL1
• Antibodie s label
  unlabelled serum
• Purity
  JAG1 antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  JAG1 antibody is human, mouse and rat reactive. At least two isoforms of JAG1 are known to exist; this antibody will detect both isoforms.
• Antigen
  JAG1 antibody was made against a 19 amino acid peptide near the carboxy terminus of human JAG1.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  JAG1 antibody can be used for detection of JAG1 by Western blot at 1 - 2 ug/ml. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  JAG1 antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  JAG1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  4557679
• Ncbi nr
  NP_000205
• KDa
  Predicted: 134 kDa Observed: 130 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  182
• GENE symbol
  JAG1
• Antigene name
  jagged 1
• Source
  homo sapiens
• Protein nr
  P78504
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  JAG1  
• Gene symbol
  JAG1
• Short name
  anti-JAG1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toJAG1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  jagged 1, AGS and AHD and AWS and CD339 and HJ1 and JAGL1, JAG1 and IDBG-54207 and ENSG00000101384 and 182, growth factor activity, Extracellular, Jag1 and IDBG-207934 and ENSMUSG00000027276 and 16449, JAG1 and IDBG-636477 and ENSBTAG00000012817 and 783681

Gene info

• Identity
  HGNC:6188
• Gene
  JAG1
• Long gene name
  jagged canonical Notch ligand 1
• Synonyms gene
  • AGS
  • JAGL1
• Synonyms gene name
  • Alagille syndrome
  • jagged 1
• Synonyms
  • AHD
  • AWS
  • HJ1
  • CD339
• GenBank acession
  • U61276
• Locus
  20p12.2
• Discovery year
  1997-05-22
• Entrez gene record
  182
• Pubmed identfication
  • 7697721
  • 9207788
• RefSeq identity
  • NM_000214
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000031872
• Locus Specific Databases
  • JAG1 database at LOVD-China
  • LRG_1191

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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