AIP1 Antibody

• Catalog number
  bs-11705R
• Price
  Please ask
• Size
  0.1ml

• Long name
  AIP1 Primary Polyclonal Antibody
• Also known as
  AIP1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  AIP1
• Specificity
  This is a highly specific antibody against AIP1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AIP1
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1,189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumor suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), implicating a role for AIP1 fusion proteins in tumorigenesis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Activin receptor interacting protein 1; Acvri1; Acvrinp1; ACVRIP1; AIP 1; Aip-1; ARIP1; Atrophin 1 interacting protein 1; Atrophin 1 interacting protein A; Atrophin-1-interacting protein 1; Atrophin-1-interacting protein A; MAGI-2; MAGI2; MAGI2_HUMAN; Membrane associated guanylate kinase 2; Membrane associated guanylate kinase inverted 2; Membrane associated guanylate kinase WW and PDZ domain containing 2; Membrane associated guanylate kinase WW and PDZ domain containing protein 2; Membrane-associated guanylate kinase; Membrane-associated guanylate kinase inverted 2; S SCAM; SSCAM; WW and PDZ domain-containing protein 2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AIP1  
• Gene symbol
  PDCD6IP, DAB2IP, ACTRT1, ARL6IP1, MAGI2
• Short name
  Anti-AIP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  AIP1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8766
• Gene
  PDCD6IP
• Long gene name
  programmed cell death 6 interacting protein
• Synonyms gene name
  • programmed cell death 6-interacting protein
• Synonyms
  • Alix
  • AIP1
  • Hp95
• Synonyms name
  • ALG-2 interacting protein X
• GenBank acession
  • BC020066
• Locus
  3p22.3
• Discovery year
  1999-12-10
• Entrez gene record
  10015
• Pubmed identfication
  • 9880530
• VEGA ID
  OTTHUMG00000130751

Gene info

• Identity
  HGNC:17294
• Gene
  DAB2IP
• Long gene name
  DAB2 interacting protein
• Synonyms
  • AF9Q34
  • DIP1/2
  • KIAA1743
  • AIP1
• Synonyms name
  • nGAP-like protein
  • DOC-2/DAB2 interactive protein
  • ASK-interacting protein
  • ASK1-interacting protein 1
• GenBank acession
  • AF367051
• Locus
  9q33.2
• Discovery year
  2002-01-23
• Entrez gene record
  153090
• Pubmed identfication
  • 11944990
  • 11812785
• RefSeq identity
  • NM_032552
• Classification
  • C2 and RasGAP domain containing
• VEGA ID
  OTTHUMG00000020595

Gene info

• Identity
  HGNC:24027
• Gene
  ACTRT1
• Long gene name
  actin related protein T1
• Synonyms
  • AIP1
  • KIAA0705
  • ARIP1
  • Arp-T1
• GenBank acession
  • AF440739
• Locus
  Xq25
• Discovery year
  2005-11-22
• Entrez gene record
  139741
• Pubmed identfication
  • 12243744
• RefSeq identity
  • NM_138289
• Classification
  • Actin related proteins
• VEGA ID
  OTTHUMG00000022359
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:697
• Gene
  ARL6IP1
• Long gene name
  ADP ribosylation factor like GTPase 6 interacting protein 1
• Synonyms gene
  • ARL6IP
• Synonyms gene name
  • ADP-ribosylation factor-like 6 interacting protein
  • ADP-ribosylation factor-like 6 interacting protein 1
• Synonyms
  • AIP1
  • ARMER
  • KIAA0069
  • SPG61
• GenBank acession
  • BC010281
• Locus
  16p12.3
• Discovery year
  2000-06-16
• Entrez gene record
  23204
• Pubmed identfication
  • 24482476
• RefSeq identity
  • NM_015161
• VEGA ID
  OTTHUMG00000131367

Gene info

• Identity
  HGNC:18957
• Gene
  MAGI2
• Long gene name
  membrane associated guanylate kinase, WW and PDZ domain containing 2
• Synonyms
  • AIP1
  • ARIP1
  • KIAA0705
  • ACVRIP1
  • MAGI-2
• Synonyms name
  • activin receptor-interacting protein 1
• GenBank acession
  • AB014605
• Locus
  7q21.11
• Discovery year
  2005-05-10
• Entrez gene record
  9863
• Pubmed identfication
  • 10681527
  • 9734811
• RefSeq identity
  • NM_012301
• Classification
  • Membrane associated guanylate kinases
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000130697

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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