Phospho-Bcl-2 (Ser70) Antibody

  • Catalog number
    A1011-100
  • Price
    Please ask
  • Size
    100µl
  • Antibody Target
    Bcl2 (Ser70)
  • Target Alternative Name
    BCL2; Apoptosis regulator Bcl-2
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, Monkey
  • Immunogen Sequence
    Synthesized peptide derived from human Bcl-2 around the phosphorylation site of Ser70
  • Accession
    P10415
  • Gene Id
    596
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    1 mg/ml
  • Formulation
    100 ug (1 mg/ml) of antibody in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
  • Purification
    Affinity purified rabbit IgG
  • Application
    WB, IHC, IP, ELISA
  • Positive Control
    Western blot
  • Application And Usages
    WB 1:500-1:2000; IHC 1:100-1:300; IP 1:200-500; ELISA 1:10000
  • Description
    Bcl2 is an integral outer mitochondrial membrane protein that regulates the apoptotic cell death in variety of cells such as lymphocytes and neural cells. It regulates mitochondrial calcium homeostasis and proton flux. Several reports suggested that these phosphorylation sites may be targets of the ASK1/MKK7/JNK1 pathway and that phosphorylation of Bcl-2 may be a marker for mitotic events. Interleukin-3 and JNK-induced Bcl-2 phosphorylation at Ser70 regulates anti-apoptotic activity.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans
  • Handling
    The antibody solution should be gently mixed before use
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    Phospho-Bcl-2 (Ser70) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    phosphorilated-Bcl-2 (Ser70) (antibody to-)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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