Phospho-Bcl-2 (Ser70) Antibody
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Catalog number
A1011-100
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Price
Please ask
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Size
100µl
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Antibody Target
Bcl2 (Ser70)
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Target Alternative Name
BCL2; Apoptosis regulator Bcl-2
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Antibody Type
Polyclonal
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Species Reactivities
Human, Monkey
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Immunogen Sequence
Synthesized peptide derived from human Bcl-2 around the phosphorylation site of Ser70
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Accession
P10415
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Gene Id
596
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Appearance
Colorless liquid
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Form
Liquid
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Concentration
1 mg/ml
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Formulation
100 ug (1 mg/ml) of antibody in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
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Purification
Affinity purified rabbit IgG
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Application
WB, IHC, IP, ELISA
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Positive Control
Western blot
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Application And Usages
WB 1:500-1:2000; IHC 1:100-1:300; IP 1:200-500; ELISA 1:10000
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Description
Bcl2 is an integral outer mitochondrial membrane protein that regulates the apoptotic cell death in variety of cells such as lymphocytes and neural cells. It regulates mitochondrial calcium homeostasis and proton flux. Several reports suggested that these phosphorylation sites may be targets of the ASK1/MKK7/JNK1 pathway and that phosphorylation of Bcl-2 may be a marker for mitotic events. Interleukin-3 and JNK-induced Bcl-2 phosphorylation at Ser70 regulates anti-apoptotic activity.
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans
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Handling
The antibody solution should be gently mixed before use
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Not Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Short name
Phospho-Bcl-2 (Ser70) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
phosphorilated-Bcl-2 (Ser70) (antibody to-)
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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